Evidence of neutralizing antibodies against SARS-CoV-2 in domestic cats living with owners with a history of COVID-19 in Lima - Peru

被引：14

作者：

Jara, Luis M. ^{[1
]}

Ferradas, Cusi ^{[2
]}

Schiaffino, Francesca ^{[1
]}

Sanchez-Carrion, Camila ^{[3
]}

Martinez-Vela, Ana ^{[4
]}

Ulloa, Alexandra ^{[3
]}

Isasi-Rivas, Gisela ^{[5
]}

Montalvan, Angela ^{[5
]}

Guevara Sarmiento, Luis ^{[5
]}

Fernandez, Manolo ^{[5
]}

Zimic, Mirko ^{[5
,6
]}

机构：

[1] Univ Peruana Cayetano Heredia, Fac Med Vet & Zootecnia, Av Honorio Delgado 430, Lima, Peru

[2] Univ Peruana Cayetano Heredia, Fac Salud Publ & Adm, Unidad Invest Enfermedades Emergentes & Cambio Cl, Lima, Peru

[3] Clin Vet Gatuario, Lima, Peru

[4] Clin Vet Los Domin, Lima, Peru

[5] Farmacol Vet FARVET, Chincha, Peru

[6] Univ Peruana Cayetano Heredia, Lab Bioinformat Biol Mol & Desarrollos Tecnol, Lima, Peru

来源：

ONE HEALTH | 2021年 / 13卷

关键词：

COVID-19; SARS-CoV-2; Cats; Serology; Neutralizing antibodies; One health;

D O I：

10.1016/j.onehlt.2021.100318

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

SARS-CoV-2 can infect a variety of wild and domestic animals worldwide. Of these, domestic cats are highly susceptible species and potential viral reservoirs. As such, it is important to investigate disease exposure in domestic cats in areas with active community transmission and high disease prevalence. In this report we demonstrate the presence of serum neutralizing antibodies against the receptor binding-domain (RBD) of the SARS-CoV-2 in cats whose owners had been infected with SARS-CoV-2 in Lima, Peru, using a commercial competitive ELISA SARS-CoV-2 Surrogate Virus Neutralization Test. Out of 41 samples, 17.1% (7/41) and 31.7% (13/41) were positive, using the cut-off inhibition value of 30% and 20%, respectively. Not all cats living in a single house had detectable neutralizing antibodies showing heterogenous exposure and immunity among cohabiting animals. This is the first report of SARS-COV-2 exposure of domestic cats in Lima, Peru. Further studies are required to ascertain the prevalence of SARS-COV-2 exposure among domestic cats.

引用

页数：5

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