Review of Heart-Lung Transplantation at Stanford

被引:24
作者
Deuse, Tobias
Sista, Ramachandra
Weill, David
Tyan, Dolly
Haddad, Francois
Dhillon, Gundeep
Robbins, Robert C.
Reitz, Bruce A. [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Cardiothorac Surg, Stanford, CA 94305 USA
关键词
BRONCHIOLITIS-OBLITERANS-SYNDROME; INTERNATIONAL-SOCIETY; CYSTIC-FIBROSIS; ORGAN-TRANSPLANTATION; PEDIATRIC LUNG; RECIPIENTS; EXPERIENCE; REJECTION; REGISTRY; CYCLOSPORINE;
D O I
10.1016/j.athoracsur.2010.01.023
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Long-term survival after heart-lung transplantation was first achieved in 1981 at Stanford and a total of 217 heart-lung transplantations had been performed by June 2008. This review summarizes Stanford's cumulative experience with heart-lung transplantation, demonstrates the progress that has been made, and discusses past and persistent problems. Diagnostic tools and treatment options for infectious diseases and rejection have changed and patient survival markedly improved over the almost three decades. Eight patients lived longer than 20 years. Further options to treat infections and strategies to control bronchiolitis obliterans syndrome, the main causes of early and long-term mortality, respectively, are required to achieve routine long-term survival. (Ann Thorac Surg 2010; 90:329-37) (C) 2010 by The Society of Thoracic Surgeons
引用
收藏
页码:329 / 337
页数:9
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