Four new chalcones from Erythrina abyssinioca

被引：17

作者：

Cui, Long ^{[2
]}

Thuong, Phuong Thien ^{[1
]}

Lee, Hyun Sun ^{[2
]}

Njamen, Dieudonne ^{[3
]}

Mbafor, Joseph Tanyi ^{[3
]}

Fomum, Z. Tanee ^{[3
]}

Lee, Junwon ^{[4
]}

Kim, Young Ho ^{[5
]}

Oh, Won Keun ^{[1
]}

机构：

[1] Chosun Univ, Coll Pharm, Kwangju 501759, South Korea

[2] KRIBB, Taejon, South Korea

[3] Yaounde I Univ, Yaounde, Cameroon

[4] Paichal Univ, Dept Gen Engn, Taejon, South Korea

[5] Chungnam Natl Univ, Coll Pharm, Taejon, South Korea

来源：

PLANTA MEDICA | 2008年 / 74卷 / 04期

关键词：

Erythrino abyssinica; Leguminosae; chalcones; cytotoxic activity;

D O I：

10.1055/s-2008-1034327

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new chalcones 1-4, named abyssinones A-D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC50 values of 13.3,15.1, and 11.1 mu M, respectively.

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收藏

页码：422 / 426

页数：5

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