Vasomotion - what is currently thought?

被引：183

作者：

Aalkjaer, C. ^{[1
]}

Boedtkjer, D. ^{[1
]}

Matchkov, V. ^{[1
]}

机构：

[1] Aarhus Univ, Dept Physiol & Biophys, Water & Salt Ctr, DK-8000 Aarhus C, Denmark

来源：

ACTA PHYSIOLOGICA | 2011年 / 202卷 / 03期

关键词：

arteries; chloride conductance; smooth muscle; SMOOTH-MUSCLE-CELLS; MESENTERIC SMALL ARTERIES; LASER-DOPPLER FLOWMETRY; VASCULAR GAP-JUNCTIONS; HAMSTER-CHEEK POUCH; INTRACELLULAR CA2+ CONCENTRATION; ISOLATED RESISTANCE ARTERIES; DEPENDENT CHLORIDE CHANNEL; CA2+-DEPENDENT CL-CHANNELS; LOW-FREQUENCY OSCILLATIONS;

D O I：

10.1111/j.1748-1716.2011.02320.x

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

This minireview discusses vasomotion, which is the oscillation in tone of blood vessels leading to flowmotion. We will briefly discuss the prevalence of vasomotion and its potential physiological and pathophysiological relevance. We will also discuss the models that have been suggested to explain how a coordinated oscillatory activity of the smooth muscle tone can occur and emphasize the role of the endothelium, the handling of intracellular Ca2+ and the role of smooth muscle cell ion conductances. It is concluded that vasomotion is likely to enhance tissue dialysis, although this concept still requires more experimental verification, and that an understanding at the molecular level for the pathways leading to vasomotion is beginning to emerge.

引用

页码：253 / 269

页数：17

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