Medical Management of Inflammatory Bowel Disease

被引:12
作者
Eichele, Derrick D. [1 ]
Young, Renee [1 ]
机构
[1] Univ Nebraska Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Omaha, NE 68198 USA
关键词
Inflammatory bowel disease; Treatment; Management; Treat-to-target strategy; Therapeutic drug monitoring; NECROSIS-FACTOR-ALPHA; ANTI-TNF THERAPY; EARLY COMBINED IMMUNOSUPPRESSION; ACTIVE ULCERATIVE-COLITIS; CROHNS-DISEASE; MAINTENANCE THERAPY; DOSE INTENSIFICATION; BIOLOGICAL AGENTS; CLINICAL-RESPONSE; INFLIXIMAB;
D O I
10.1016/j.suc.2019.08.011
中图分类号
R61 [外科手术学];
学科分类号
摘要
Inflammatory bowel disease has become a growing concern worldwide. The chronic and progressive nature of inflammatory bowel disease poses significant challenges to the treatment and management of affected patients, straining health care resources. Therapeutic options and optimal management strategies have evolved dramatically. The treat-to-target strategy has shifted focus toward identifiable and attainable treatment targets and with the ability to optimize tight control. Advancements in our understanding of the pathophysiology led to therapeutic mechanisms that have a more narrowed focus toward gut-specific targets, improving safety profiles.
引用
收藏
页码:1223 / +
页数:14
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