Microwave-Assisted Synthesis of 2,4,5-Triphenyl-1H-imidazole Containing Schiff Base Derivatives with Potential Antioxidant and Anticancer Activities

被引:0
作者
Satyanarayana, V. S. V. [1 ]
Rakshit, Madhumita [2 ]
Sivakumar, A. [1 ]
机构
[1] VIT Univ, Sch Adv Sci, Div Chem, Vellore 632014, Tamil Nadu, India
[2] VIT Univ, Sch Biosci & Technol, Vellore 632014, Tamil Nadu, India
关键词
Schiff base; 2,4,5-Triphenyol-1H-imidazole; Microwave irradiation; Antioxidant activity; Anticancer activity; ANTIMICROBIAL ACTIVITY; ORGANIC-SYNTHESIS; INHIBITORS; IMIDAZOLE; AMARYLLIDACEAE; SCELETIUM; ALKALOIDS; THIAZOLE; OXAZOLE; OVENS;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
2-(2,4,5-Triphenyl-1H-imidazol-1-yl)acetohydrazide (3) was utilized as key intermediate for the synthesis of some new Schiff bases 4a-k and 5 under reflux temperature as well as microwave irradiation. All the synthesized compounds were characterized by IR, H-1 NMR, C-13 NMR and HRMS spectral studies. The antioxidant and anticancer activities of these newly synthesized Schiff base derivatives containing 2,4,5-triphenyl-1H-imidazole moiety have been evaluated.
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页码:1212 / 1218
页数:7
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