Misuse of corticosteroids in some of the drugs dispensed as preparations from alternative systems of medicine in India

被引:21
作者
Gupta, SK [1 ]
Kaleekal, T [1 ]
Joshi, S [1 ]
机构
[1] All India Inst Med Sci, Dept Pharmacol, New Delhi 110029, India
关键词
corticosteroids; adverse effects; alternate systems of medicine; ayurvedic; homeopathic; asthma; arthritis;
D O I
10.1002/pds.553
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Screening for corticosteroids carried out on 120 samples of alternative medicines which were dispensed to patients suffering mainly from asthma, arthritis, etc., showed that 38.32% of them were adulterated with steroids. Most of these samples were submitted for screening by either a medical practitioner or the patients themselves, who suspected effects of steroids from these drugs. The percentage of steroid positivity was determined in ayurvedic drugs, homeopathic drugs, and unknown or other category of drugs. The presence of steroids in these drugs given for different ailments such as asthma, arthritis, and unknown/other ailments was also tabulated. The results show that a high percentage of these samples contained corticosteroids, however, the distribution of positivity amongst groups was not statistically significant. The lack of proper quality control mechanisms to verify ingredients or efficacy of 'alternative medicines' has led to the proliferation of the practice of dispensing spurious drugs containing corticosteroids as alternative medicines. This study aims to highlight the existence of 'quick fix' remedies dispensed as 'alternative medicines' which not only cause extensive adverse health effects to the patients but also bring alternative systems of medicines into disrepute. The deliberate contamination of corticosteroids with alternative systems of medicine by some practitioners is a cause of great concern. Such practices may not only disgrace alternative systems of medicine but may also lead to adverse side-effects on chronic exposure. Copyright (C) 2000 John Wiley & Sons, Ltd.
引用
收藏
页码:599 / 602
页数:4
相关论文
共 10 条
[1]  
BASU N, 1984, Indian Journal of Physiology and Pharmacology, V28, P170
[2]  
FREYBERG RH, 1951, JAMA-J AM MED ASSOC, V47, P1538
[3]  
HASKETT RF, 1985, AM J PSYCHIAT, V142, P911
[4]  
KEANE FM, 1999, BRIT MED J, V318, P363
[5]  
Limbird LE., 1996, GOODMAN GILMANS PHAR
[6]  
MOFENSON HC, 1988, EMERGENCY TOXICOLOGY, P1184
[7]   CLINICAL AND PHYSIOLOGIC IMPLICATIONS OF THE STEROID-INDUCED PEPTIC ULCER [J].
SPIRO, HM ;
MILLES, SS .
NEW ENGLAND JOURNAL OF MEDICINE, 1960, 263 (06) :286-294
[8]   SECONDARY MANIA WITH STEROID WITHDRAWAL [J].
VENKATARANGAM, SHM ;
KUTCHER, SP ;
NOTKIN, RM .
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 1988, 33 (07) :631-632
[9]   LONG-LASTING BEHAVIORAL-CHANGES FOLLOWING PREDNISONE WITHDRAWAL [J].
WOLKOWITZ, OM ;
RAPAPORT, M .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 261 (12) :1731-1732
[10]  
Ziment I, 2000, Curr Opin Pulm Med, V6, P71, DOI 10.1097/00063198-200001000-00013