Treatment of Alzheimer's disease - New developments

被引:0
作者
Giacobini, E [1 ]
Michel, JP [1 ]
机构
[1] Univ Hosp Geneva, Dept Geriatr, Geneva Med Sch, CH-1226 Geneva, Switzerland
来源
ANNALES DE MEDECINE INTERNE | 1998年 / 149卷 / 04期
关键词
Alzheimer's disease; Cholinesterase inhibitors;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cholinesterase inhibitors (ChEI) represent the drug of choice for Alzheimer's disease treatment. They produce significant improvement on cognitive as well as non-cognitive function for a period up to one year during the first three years period following clinical onset. The magnitude of cognitive improvements is similar for different ChEI; however, differences are seen with regard to incidence and severity of side effects, incidence of drop-outs, optimal ChE inhibition, pharmacokinetics properties and mode of administration.
引用
收藏
页码:231 / 237
页数:7
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