The effects of intravenous lidocaine on pain during injection of medium- and long-chain triglyceride propofol emulsions

被引：22
|
作者：
Yew, WS [1 ]
Chong, SY [1 ]
Tan, KH [1 ]
Goh, MH [1 ]
机构：
[1] Singapore Gen Hosp, Dept Anaesthesia & Surg Intens Care, Singapore 169608, Singapore
来源：
ANESTHESIA AND ANALGESIA | 2005年 / 100卷 / 06期
关键词：
D O I：
10.1213/01.ANE.0000151718.58709.0B
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Propofol formulated in medium- and long-chain triglycerides (MCT/LCT) is thought to cause less pain on injection. In this study we sought to determine if adding lidocaine to propofol-MCT/LCT is more effective in decreasing pain compared with propofol-MCT/ LCT alone or conventional propofol-lidocaine mixtures. Seventy-five patients were randomized into three groups. Group A received conventional propofol-lidocaine mixtures with 20 mg lidocaine, group B received propofol-MCT/LCT with saline, and group C received propofol-MCT/LCT with 20 mg lidocaine. The incidence of pain was 24% in groups A and B and 4% in group C. The number needed to treat to prevent pain was 5. We conclude that propofol-MCT/LCT-lidocaine mixtures significantly reduce pain.
引用
收藏
页码：1693 / 1695
页数：3
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