Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants

被引:0
|
作者
Tang, Honghai [1 ,2 ,3 ,4 ,5 ]
Wang, Daqi [1 ,2 ,3 ,4 ,5 ]
Shu, Yilai [1 ,2 ,3 ,4 ,5 ]
机构
[1] Fudan Univ, ENT Inst, Shanghai, Peoples R China
[2] Fudan Univ, Dept Otorhinolaryngol, Eye & ENT Hosp, State Key Lab Med Neurobiol, Shanghai, Peoples R China
[3] Fudan Univ, MOE Frontiers Ctr Brain Sci, Shanghai, Peoples R China
[4] Fudan Univ, Inst Biomed Sci, Shanghai, Peoples R China
[5] Fudan Univ, NHC Key Lab Hearing Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
NUCLEASES;
D O I
10.1038/s41392-022-01139-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:3
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