Fornix based trabeculectomy with Wise's suture technique in Chinese patients

Objective: To assess the safety and efficacy of fornix-based trabeculectomy with Wise's suture technique in Chinese subjects. Design: A retrospective noncomparative case series. Participants: Forty-eight eyes of 44 Chinese subjects that underwent fornix-based trabeculectomy combined with intraoperative 0.4 mg/ml mitomycin-C for 3 to 5 minutes were studied. Intervention: Conjunctival wound closure of all eyes was with the Wise's technique using 9-0 nylon suture to prevent leakage at the corneolimbal interface. Main Outcome Measures The success rate, with or without antiglaucoma medication, the complication rate, and the longevity of the drainage blebs were analyzed. Results: At a mean follow-up period of 21.8 +/- 4.5 months, 75% (36 eyes) had postoperative intraocular pressure of 21 mmHg or less. Of these, 23 eyes (47.9%) required no antiglaucoma medication, 7 eyes (14.6%) required one medication, 3 eyes (6.3%) required two medications, and 3 eyes (6.3%) required three medications. Ten eyes (21%) had early wound leak. Two eyes (4.2%) required surgical repair. Two eyes (4%) had hypotonous maculopathy. No other major complications were encountered. Conclusions Fornix-based trabeculectomy with adjunctive mitomycin-G using Wise's suture technique appears to be both safe and effective in Chinese subjects. (C) 2000 by the American Academy of Ophthalmology.