Liquid chromatography-mass spectrometry analysis of propolis

被引：81

作者：

Midorikawa, K

Banskota, AH

Tezuka, Y

Nagaoka, T

Matsushige, K

Message, D

Huertas, AAG

Kadota, S ^{[1
]}

机构：

[1] Toyama Med & Pharmaceut Univ, Inst Nat Med, Dept Nat Prod Chem, Sugitani, Toyama 9300194, Japan

[2] Univ Fed Vicosa, Dept Biol Anim, BR-36571000 Vicosa, MG, Brazil

来源：

PHYTOCHEMICAL ANALYSIS | 2001年 / 12卷 / 06期

关键词：

liquid chromatography-mass spectrometry; phenolic compounds; diterpenes; propolis; Baccharis dracunculitolia;

D O I：

10.1002/pca.605

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The composition of propolis, a resinous hive product collected by honeybees from various plant sources, depends on various factors such as season and vegetation or the area. Based on standards (either isolated from Brazilian propolis or reported from propolis) including chromane, diterpenes and phenolic compounds, different Brazilian propolis were analysed by LC-MS in order to determine their chemical constituents. Dicaffeoylquinic acids were detected in almost all water extracts of Brazilian propolis, whereas diterpenes, flavonoids and prenylated phenolic compounds were found in their methanol extracts. Based on the identified chemical constituents and their biological activities, it was determined that the quality of Brazilian propolis could be directly related to the phenolic constituents. Moreover, Baccharis dracunculifolia Nas concluded to be an important source or Brazilian propolis. Propolis samples from Peru, China and the Netherlands were also studied. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：366 / 373

页数：8

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