Inner retinal metabolic rate of oxygen by oxygen tension and blood flow imaging in rat

被引：0

作者：

Wanek, Justin ^{[1
]}

Teng, Pang-yu ^{[1
]}

Albers, John ^{[1
]}

Blair, Norman P. ^{[1
]}

Shahidi, Mahnaz ^{[1
]}

机构：

[1] Univ Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL 60612 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 09期

关键词：

OPTICAL COHERENCE TOMOGRAPHY; LEUKOCYTE DYNAMICS; CONSUMPTION; VELOCITY; CIRCULATION; RETINOPATHY; SATURATION; HYPEROXIA; OCCLUSION; HYPOXIA;

D O I：

10.1364/BOE.2.002562

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The metabolic function of inner retinal cells relies on the availability of nutrients and oxygen that are supplied by the retinal circulation. Assessment of retinal tissue vitality and function requires knowledge of both the rate of oxygen delivery and consumption. The purpose of the current study is to report a novel technique for assessment of the inner retinal metabolic rate of oxygen (MO2) by combined measurements of retinal blood flow and vascular oxygen tension (PO2) in rat. The application of this technology has the potential to broaden knowledge of retinal oxygen dynamics and advance understanding of disease pathophysiology. (C) 2011 Optical Society of America

引用

页码：2562 / 2568

页数：7

共 36 条

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