Memory in paediatric temporal lobe epilepsy: Effects of lesion type and side

被引:28
作者
Cormack, Francesca [1 ]
Vargha-Khadem, Faraneh [1 ]
Wood, Stephen J. [2 ,3 ,4 ]
Cross, J. Helen [5 ,6 ]
Baldeweg, Torsten [1 ]
机构
[1] UCL Inst Child Hlth, Dev Cognit Neurosci Unit, London, England
[2] Univ Birmingham, Sch Psychol, Birmingham B15 2TT, W Midlands, England
[3] Univ Melbourne, Dept Psychiat, Melbourne Neuropsychiat Ctr, Melbourne, Vic 3010, Australia
[4] Melbourne Hlth, Melbourne, Vic, Australia
[5] UCL Inst Child Hlth, Neurosci Unit, London, England
[6] Great Ormond St Hosp Sick Children, London WC1N 3JH, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
Memory; Paediatric; Temporal lobe epilepsy; Hippocampus; DNT; DEVELOPMENTAL AMNESIA; SEMANTIC MEMORY; VERBAL MEMORY; CHILDREN; CHILDHOOD; DEFICITS; SURGERY;
D O I
10.1016/j.eplepsyres.2011.09.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This study investigated the role of underlying pathology on memory function of children with temporal lobe epilepsy (TLE). Memory was assessed in 44 children with TLE resulting from hippocampal sclerosis (HS) or dysembryoplastic neuroepithelial tumours (DNT), and 22 control children. Delayed story and paired associate recall performance was significantly more impaired in children with HS compared to those with DNT, irrespective of the affected side. Semantic memory was impaired in both HS groups, and also in the left DNT group. These results suggest a role for type, and to a lesser extent, side of pathology in the memory profile of children with TLE. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:255 / 259
页数:5
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