Epidemiology of Pediatric Convulsive Status Epilepticus With Fever in the Emergency Department: A Cohort Study of 381 Consecutive Cases

被引:12
作者
Hayakawa, Itaru [1 ]
Miyama, Sahoko [1 ,2 ]
Inoue, Nobuaki [3 ]
Sakakibara, Hiroshi [1 ]
Hataya, Hiroshi [1 ]
Terakawa, Toshiro [1 ]
机构
[1] Tokyo Metropolitan Childrens Med Ctr, Dept Gen Pediat, Musashidai 2-8-29, Fuchu, Tokyo 1838561, Japan
[2] Tokyo Metropolitan Childrens Med Ctr, Dept Neurol, Tokyo, Japan
[3] Tokyo Metropolitan Childrens Med Ctr, Div Pediat Emergency Med, Dept Pediat Emergency & Crit Care Med, Tokyo, Japan
关键词
convulsive status epilepticus; prolonged febrile seizure; encephalopathy; encephalitis; epilepsy; meningitis; ACUTE ENCEPHALOPATHY; CHILDREN; INHIBITION; INFLUENZA; SEIZURES;
D O I
10.1177/0883073816652234
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Pediatric convulsive status epilepticus with fever is common in the emergency setting but leads to severe neurological sequelae in some patients. To explore the epidemiology of convulsive status epilepticus with fever, a retrospective cohort covering all convulsive status epilepticus cases with fever seen in the emergency department of a tertiary care children's hospital were consecutively collected. Of the 381 consecutive cases gathered, 81.6% were due to prolonged febrile seizure, 6.6% to encephalopathy/encephalitis, 0.8% to meningitis, and 7.6% to epilepsy. In addition, seizures were significantly longer in encephalopathy/encephalitis cases than in prolonged febrile seizure cases (log rank test, P < .001). These results provide for the first time the pretest probability of final diagnoses in children with convulsive status epilepticus with fever in the emergency setting, and will help optimize the management of pediatric patients presenting to the emergency department with convulsive status epilepticus with fever.
引用
收藏
页码:1257 / 1264
页数:8
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