Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth

被引:141
|
作者
Gavrias, V
Andrianopoulos, A
Gimeno, CJ
Timberlake, WE
机构
[1] MYCO PHARMACEUT INC, CAMBRIDGE, MA 02139 USA
[2] UNIV GEORGIA, DEPT GENET, ATHENS, GA 30602 USA
[3] MIT, WHITEHEAD INST BIOMED RES, CAMBRIDGE, MA 02142 USA
关键词
D O I
10.1111/j.1365-2958.1996.tb02470.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Diverse eukaryotic organisms share developmental transcription factors with homologous DNA-binding domains. We showed that the developmental regulator AbaA, a member of the ATTS/TEA ((A) under bar b(a)A, (T) under bar EF-1, (T) under bar EC1, Scalloped/(T) under bar EF-1, (T) under bar EC1, (A) under bar baA) class of transcription factors of the filamentous fungus Aspergillus nidulans, induces pseudohyphal development in the yeast Saccharomyces cerevisiae. The S. cerevisiae homologue of AbaA, TEC1p, is required for this morphological transition. We provide evidence that TEC1p functions in co-operation with STE12p to induce pseudohyphal development.
引用
收藏
页码:1255 / 1263
页数:9
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