Texturing of titanium (Ti6Al4V) medical implant surfaces with MHz-repetition-rate femtosecond and picosecond Yb-doped fiber lasers

被引:58
作者
Erdogan, Mutlu [1 ]
Oktem, Bulent [1 ]
Kalaycioglu, Hamit [2 ]
Yavas, Seydi [1 ]
Mukhopadhyay, Pranab K. [2 ]
Eken, Koray [3 ]
Ozgoren, Kivanc [1 ]
Aykac, Yasar [4 ]
Tazebay, Uygar H. [5 ,6 ]
Ilday, F. Omer [2 ]
机构
[1] Bilkent Univ, Mat Sci & Nanotechnol Grad Program, TR-06800 Ankara, Turkey
[2] Bilkent Univ, Dept Phys, TR-06800 Ankara, Turkey
[3] FiberLAST Ltd, TR-06531 Ankara, Turkey
[4] Ankara Univ, Fac Dent, TR-06100 Ankara, Turkey
[5] Bilkent Univ, Mol Biol & Genet Dept, TR-06800 Ankara, Turkey
[6] Bilkent Univ, BILGEN, Genet & Biotechnol Res Ctr, TR-06800 Ankara, Turkey
关键词
CELLS; PROLIFERATION; ATTACHMENT; GUIDANCE; CONTACT; SAOS-2;
D O I
10.1364/OE.19.010986
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We propose and demonstrate the use of short pulsed fiber lasers in surface texturing using MHz-repetition-rate, microjoule- and sub-microjoule-energy pulses. Texturing of titanium-based (Ti6Al4V) dental implant surfaces is achieved using femtosecond, picosecond and (for comparison) nanosecond pulses with the aim of controlling attachment of human cells onto the surface. Femtosecond and picosecond pulses yield similar results in the creation of micron-scale textures with greatly reduced or no thermal heat effects, whereas nanosecond pulses result in strong thermal effects. Various surface textures are created with excellent uniformity and repeatability on a desired portion of the surface. The effects of the surface texturing on the attachment and proliferation of cells are characterized under cell culture conditions. Our data indicate that picosecond-pulsed laser modification can be utilized effectively in low-cost laser surface engineering of medical implants, where different areas on the surface can be made cell-attachment friendly or hostile through the use of different patterns. (C) 2011 Optical Society of America
引用
收藏
页码:10986 / 10996
页数:11
相关论文
共 31 条
[1]   Surface characterization of poly(methyl methacrylate) microgrooved for contact guidance of mammalian cells [J].
Alaerts, JA ;
De Cupere, VM ;
Moser, S ;
de Aguilar, PVB ;
Rouxhet, PG .
BIOMATERIALS, 2001, 22 (12) :1635-1642
[2]   On the theory of ultrashort laser pulse interaction with a metal [J].
Anisimov, SI ;
Rethfeld, B .
NONRESONANT LASER-MATTER INTERACTION (NLMI-9), 1997, 3093 :192-203
[3]   Osteoblast adhesion on biomaterials [J].
Anselme, K .
BIOMATERIALS, 2000, 21 (07) :667-681
[4]  
Brånemark R, 2001, J REHABIL RES DEV, V38, P175
[5]  
Buser D, 1999, J BIOMED MATER RES, V45, P75, DOI 10.1002/(SICI)1097-4636(199905)45:2<75::AID-JBM1>3.0.CO
[6]  
2-P
[7]   All-normal-dispersion femtosecond fiber laser [J].
Chong, Andy ;
Buckley, Joel ;
Renninger, Will ;
Wise, Frank .
OPTICS EXPRESS, 2006, 14 (21) :10095-10100
[8]   Effects of roughness, fibronectin and vitronectin on attachment, spreading, and proliferation of human osteoblast-like cells (Saos-2) on titanium surfaces [J].
Degasne, I ;
Baslé, MF ;
Demais, V ;
Huré, G ;
Lesourd, M ;
Grolleau, B ;
Mercier, L ;
Chappard, D .
CALCIFIED TISSUE INTERNATIONAL, 1999, 64 (06) :499-507
[9]   Laser microfabricated model surfaces for controlled cell growth [J].
Duncan, AC ;
Weisbuch, F ;
Rouais, F ;
Lazare, S ;
Baquey, C .
BIOSENSORS & BIOELECTRONICS, 2002, 17 (05) :413-426
[10]   State of the art in laser surface texturing [J].
Etsion, I .
JOURNAL OF TRIBOLOGY-TRANSACTIONS OF THE ASME, 2005, 127 (01) :248-253