HIV point-of-care testing pitfalls

被引:0
作者
Chan, S. Y. [1 ]
Wyld, C. [1 ]
Rice, P. [1 ]
Lau, R. [1 ]
机构
[1] St George Hosp, Courtyard Clin, London, England
关键词
HIV; postexposure prophylaxis; PEPSE; HIV testing; point-of-care test; POSTEXPOSURE PROPHYLAXIS; INFECTION;
D O I
10.1258/ijsa.2011.011145
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
When counselling patients for postexposure prophylaxis after sexual exposure, we may need to inform them that the efficacy may be low, especially if the patient also had risks prior to the 72 hours between exposure and treatment. The use of a point-of-care test, as well as fourth generation HIV tests and HIV RNA in combination, can still miss seroconversion in the 'eclipse' phase of the infection as these tests are not designed to detect the earliest phase of infection.
引用
收藏
页码:764 / 765
页数:2
相关论文
共 8 条
[1]   The National Blood Service (England) approach to evaluation of kits for detecting infectious agents [J].
Barbara, John ;
Ramskill, Steve ;
Perry, Keith ;
Parry, John ;
Nightingale, Mark .
TRANSFUSION MEDICINE REVIEWS, 2007, 21 (02) :147-158
[2]   MEDICAL PROGRESS Acute HIV-1 Infection [J].
Cohen, Myron S. ;
Shaw, George M. ;
McMichael, Andrew J. ;
Haynes, Barton F. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (20) :1943-1954
[3]   UK Guideline for the use of post-exposure prophylaxis for HIV following sexual exposure [J].
Fisher, M ;
Benn, P ;
Evans, B ;
Pozniak, A ;
Jones, M ;
MacLean, S ;
Davidson, O ;
Summerside, J ;
Hawkins, D .
INTERNATIONAL JOURNAL OF STD & AIDS, 2006, 17 (02) :81-92
[4]   Low rates of p24 antigen detection using a fourth-generation point of care HIV test [J].
Fox, Julie ;
Dunn, Helen ;
O'Shea, Siobhan .
SEXUALLY TRANSMITTED INFECTIONS, 2011, 87 (02) :178-179
[5]   Seroconversion following nonoccupational postexposure prophylaxis against HIV [J].
Roland, ME ;
Neilands, TB ;
Krone, MR ;
Katz, MH ;
Franses, K ;
Grant, RM ;
Busch, MP ;
Hecht, FM ;
Shacklett, BL ;
Kahn, JO ;
Bamberger, JD ;
Coates, TJ ;
Chesney, MA ;
Martin, JN .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (10) :1507-1513
[6]  
Siemens Healthcare Diagnostics Inc, 2008, ADVIA CENT ADVIA CEN
[7]   Screening for acute HIV infection: Lessons learned [J].
Stekler, Joanne ;
Maenza, Janine ;
Stevens, Claire E. ;
Swenson, Paul D. ;
Coombs, Robert W. ;
Wood, Robert W. ;
Campbell, Mary S. ;
Nickle, David C. ;
Collier, Ann C. ;
Golden, Matthew R. .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (03) :459-461
[8]   BASHH Clinical Governance Committee guidance on the appropriate use of HIV point of care tests [J].
Winter, A. J. ;
Sulaiman, Z. ;
Hawkins, D. .
INTERNATIONAL JOURNAL OF STD & AIDS, 2006, 17 (12) :802-805