Wharton's Jelly stem cells: Future clinical applications

被引：121

作者：

Taghizadeh, R. R. ^{[1
]}

Cetrulo, K. J. ^{[1
]}

Cetrulo, C. L. ^{[1
]}

机构：

[1] AuxoCell Labs Inc, Cambridge, MA 02142 USA

来源：

PLACENTA | 2011年 / 32卷

关键词：

Mesenchymal stem cells; Umbilical cord blood; Umbilical cord tissue; Wharton's Jelly stem cells; Stem cells; Mesenchymal stromal cells; HUMAN UMBILICAL-CORD; MESENCHYMAL STROMAL CELLS; GENE-THERAPY; RODENT MODEL; BLOOD; TRANSPLANTATION; FETAL; DIFFERENTIATION; IDENTIFICATION; GROWTH;

D O I：

10.1016/j.placenta.2011.06.010

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This review focuses on the therapeutic potential of stem cells harvested from the Wharton's Jelly of the human umbilical cord. Recently, investigators have found that a potent stem cell population exists within the Wharton's Jelly. In this review, the authors define a new subset of stem cells, termed perinatal stem cells, and compare them to other sources of stem cells. Furthermore, cryopreservation of Wharton's Jelly stem cells is described for potential use in future cell based therapies and/or regenerative medicine applications. Current evidence of the application of mesenchymal stem cells from various sources in both pre-clinical and clinical trials is reviewed in the context of potential indications of use for Wharton's Jelly derived mesenchymal stem cells. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：S311 / S315

页数：5

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