Discovery and Enumeration of Organic-Chemical and Biomimetic Reaction Cycles within the Network of Chemistry

被引：14

作者：

Bajczyk, Michal D. ^{[1
]}

Dittwald, Piotr ^{[1
]}

Wolos, Agnieszka ^{[1
]}

Szymkuc, Sara ^{[1
]}

Grzybowski, Bartosz A. ^{[1
,2
,3
]}

机构：

[1] Polish Acad Sci, Inst Organ Chem, Ul Kasprzaka 44-52, PL-01224 Warsaw, Poland

[2] UNIST, IBS Ctr Soft & Living Matter, 50 UNIST Gil, Ulsan, South Korea

[3] UNIST, Dept Chem, 50 UNIST Gil, Ulsan, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 09期

关键词：

big-data analysis; chemical networks; cliques; cycles; organic synthesis; SYSTEMS CHEMISTRY; BIOSYNTHESIS; ARGININE;

D O I：

10.1002/anie.201712052

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Analysis of the chemical-organic knowledge represented as a giant network reveals that it contains millions of reaction sequences closing into cycles. Without realizing it, independent chemists working at different times have jointly created examples of cyclic sequences that allow for the recovery of useful reagents and for the autoamplification of synthetically important molecules, those that mimic biological cycles, and those that can be operated one-pot.

引用

页码：2367 / 2371

页数：5

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