One-Pot Synthesis of Asymmetric Annulated Bis(pyrrole)s

被引：9

作者：

Smithen, Deborah A. ^{[1
]}

Cameron, T. Stanley ^{[1
]}

Thompson, Alison ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4R2, Canada

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 21期

基金：

加拿大自然科学与工程研究理事会;

关键词：

PYRROLE;

D O I：

10.1021/ol202457n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of activated functionalized pyrroles with acetone results in asymmetric bis(pyrrole)s, formed via ring annulation. The methodology Is somewhat general and can be applied to a variety of ketones, as well as to a range of pyrrolic substrates that do not bear electron-withdrawing groups directly adjacent to the pyrrole ring.

引用

页码：5846 / 5849

页数：4

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