Impacts of food contact chemicals on human health: a consensus statement

被引：147

作者：

Muncke, Jane ^{[1
]}

Andersson, Anna-Maria ^{[2
]}

Backhaus, Thomas ^{[3
]}

Boucher, Justin M. ^{[4
]}

Almroth, Bethanie Carney ^{[3
]}

Castillo, Arturo Castillo ^{[5
]}

Chevrier, Jonathan ^{[6
]}

Demeneix, Barbara A. ^{[7
,8
]}

Emmanuel, Jorge A. ^{[9
]}

Fini, Jean-Baptiste ^{[7
,8
]}

Gee, David ^{[10
]}

Geueke, Birgit ^{[1
]}

Groh, Ksenia ^{[1
]}

Heindel, Jerrold J. ^{[11
]}

Houlihan, Jane ^{[12
]}

Kassotis, Christopher D. ^{[13
]}

Kwiatkowski, Carol F. ^{[14
]}

Lefferts, Lisa Y. ^{[15
]}

Maffini, Maricel V.

Martin, Olwenn V. ^{[16
]}

Myers, John Peterson ^{[17
,18
]}

Nadal, Angel ^{[19
,20
]}

Nerin, Cristina ^{[21
]}

Pelch, Katherine E. ^{[14
]}

Fernandez, Seth Rojello ^{[22
]}

Sargis, Robert M. ^{[23
]}

Soto, Ana M. ^{[24
]}

Trasande, Leonardo ^{[25
]}

Vandenberg, Laura N. ^{[26
]}

Wagner, Martin ^{[27
]}

Wu, Changqing ^{[28
]}

Zoeller, R. Thomas ^{[29
]}

Scheringer, Martin ^{[4
,30
]}

机构：

[1] Food Packaging Forum Fdn, Zurich, Switzerland

[2] Univ Copenhagen, Int Ctr Res & Res Training Endocrine Disrupt Male, Dept Growth & Reprod, Rigshosp, Copenhagen, Denmark

[3] Univ Gothenburg, Dept Biol & Environm Sci, Gothenburg, Sweden

[4] Swiss Fed Inst Technol, Inst Biogeochem & Pollutant Dynam, Zurich, Switzerland

[5] Imperial Coll London, Ctr Environm Policy, London, England

[6] McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Fac Med, Montreal, PQ, Canada

[7] CNRS, French Natl Res Ctr, UMR 7221, Dept Adaptat Vivant, Paris, France

[8] Museum Natl Hist Nat, Paris, France

[9] Silliman Univ, Inst Environm & Marine Sci, Dumaguete, Philippines

[10] Brunel Univ, Inst Environm Hlth & Soc, Uxbridge, Middx, England

[11] Commonweal, Hlth Environm & Endocrine Disruptor Strategies, Bolinas, CA USA

[12] Hlth Babies Bright Futures, Charlottesville, VA USA

[13] Duke Univ, Nicholas Sch Environm, Durham, NC 27708 USA

[14] Endocrine Disrupt Exchange, Eckert, CO USA

[15] Ctr Sci Publ Interest, Washington, DC USA

[16] Brunel Univ London, Inst Environm Hlth & Soc, Uxbridge, Middx, England

[17] Environm Hlth Sci, Charlottesville, VA USA

[18] Carnegie Mellon Univ, Dept Chem, 4400 5th Ave, Pittsburgh, PA 15213 USA

[19] Univ Miguel Hernandez, IDiBE, Elche, Spain

[20] Univ Miguel Hernandez, CIBERDEM, Elche, Spain

[21] Univ Zaragoza, I3A, Zaragoza, Spain

[22] Green Sci Policy Inst, Berkeley, CA USA

[23] Univ Illinois, Dept Med, Div Endocrinol Diabet & Metab, Chicago, IL USA

[24] Tufts Univ, Sch Med, Dept Immunol, Boston, MA 02111 USA

[25] NYU, Dept Pediat, Grossman Sch Med, New York, NY 10016 USA

[26] Univ Massachusetts, Dept Environm Hlth Sci, Sch Publ Hlth & Hlth Sci, Amherst, MA 01003 USA

[27] Norwegian Univ Sci Technol NTNU, Dept Biol, Trondheim, Norway

[28] Univ Delaware, Dept Anim & Food Sci, Newark, DE USA

[29] Univ Massachusetts, Dept Biol, Amherst, MA 01003 USA

[30] Masaryk Univ, RECETOX, Brno, Czech Republic

来源：

ENVIRONMENTAL HEALTH | 2020年 / 19卷 / 01期

关键词：

Food contact material; Migration; Food packaging; Non-intentionally added substance; Chronic disease; Human health; Mixture toxicity; Endocrine disrupting chemical; Sustainable packaging; Circular economy; ENDOCRINE-DISRUPTING CHEMICALS; PACKAGING MATERIALS; BISPHENOL-A; SAFETY ASSESSMENT; BOTTLED WATERS; ISOPROPYLTHIOXANTHONE ITX; URINARY CONCENTRATIONS; POTENTIAL MIGRANTS; POLYMER ADDITIVES; RISK-ASSESSMENT;

D O I：

10.1186/s12940-020-0572-5

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Food packaging is of high societal value because it conserves and protects food, makes food transportable and conveys information to consumers. It is also relevant for marketing, which is of economic significance. Other types of food contact articles, such as storage containers, processing equipment and filling lines, are also important for food production and food supply. Food contact articles are made up of one or multiple different food contact materials and consist of food contact chemicals. However, food contact chemicals transfer from all types of food contact materials and articles into food and, consequently, are taken up by humans. Here we highlight topics of concern based on scientific findings showing that food contact materials and articles are a relevant exposure pathway for known hazardous substances as well as for a plethora of toxicologically uncharacterized chemicals, both intentionally and non-intentionally added. We describe areas of certainty, like the fact that chemicals migrate from food contact articles into food, and uncertainty, for example unidentified chemicals migrating into food. Current safety assessment of food contact chemicals is ineffective at protecting human health. In addition, society is striving for waste reduction with a focus on food packaging. As a result, solutions are being developed toward reuse, recycling or alternative (non-plastic) materials. However, the critical aspect of chemical safety is often ignored. Developing solutions for improving the safety of food contact chemicals and for tackling the circular economy must include current scientific knowledge. This cannot be done in isolation but must include all relevant experts and stakeholders. Therefore, we provide an overview of areas of concern and related activities that will improve the safety of food contact articles and support a circular economy. Our aim is to initiate a broader discussion involving scientists with relevant expertise but not currently working on food contact materials, and decision makers and influencers addressing single-use food packaging due to environmental concerns. Ultimately, we aim to support science-based decision making in the interest of improving public health. Notably, reducing exposure to hazardous food contact chemicals contributes to the prevention of associated chronic diseases in the human population.

引用

页数：12

共 140 条

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