Salt taste threshold, 24 hour natriuresis and blood pressure variation in normotensive individuals

被引:9
作者
Antonello, Vicente Sperb [1 ]
Ferreira Antonello, Ivan Carlos [1 ]
De Los Santos, Carlos Abaete [1 ]
机构
[1] Pontificia Univ Catolica Rio Grande do Sul, Fac Med, Trabalho Realizado Dept Med Interna, Porto Alegre, RS, Brazil
来源
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA | 2007年 / 53卷 / 02期
关键词
taste threshold; sodium chloride; blood pressure;
D O I
10.1590/S0104-42302007000200019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE. The study evaluates salt taste sensibility, urinary sodium excretion and blood pressure (BP) in normotensive persons, The hypothesis was that a higher salt taste threshold (STT) can be associated to a higher 24 hour natriuresis and increased BP levels. METHODS, Twenty four not hypertensive volunteers were selected. To evaluate STT, different concentrations of sodium chloride were used, Individuals were submitted to 24 hour ambulatory blood pressure monitoring (ABPM) and the 24 hour urine was collected for sodium dosage. Patients were divided in two groups related to higher or normal STT. RESULTS. Both groups did not differ regarding age or body moss index (BMI). There was no difference between the groups regarding demographic variables, alcohol or tobacco use, and ABPM. Twenty-four hour natriuresis was significantly higher in the group with increased STT. Using Pearson's correlation coefficient, with the significance determined by Student-t test, there was 0 strong correlation between 24 hour Systolic BP and BMI, Diastolic BP and BMI, and a regular correlation between STT with 24 hour natriuresis and Systolic BP with 24 hour natriuresis, CONCLUSION. Twenty four hour natriuresis was significantly higher in individuals with higher STT, suggesting that this avidity for salt is followed by higher ingestion of sodium. There was strong association between BP and BMI. The association between STT and BP levels was not confirmed. Increasing the number of persons, the age bracket, and of hypertensive patients may lead to a better understanding of the relations between STT, natriuresis and BP variation.
引用
收藏
页码:142 / 146
页数:5
相关论文
共 17 条
[1]  
[Anonymous], 2004, COCHRANE DB SYST REV, DOI DOI 10.1002/14651858.CD004937
[2]   The epidemiology of salt and hypertension [J].
Beevers, DG .
CLINICAL AUTONOMIC RESEARCH, 2002, 12 (05) :353-357
[3]   Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].
Chobanian, AV ;
Bakris, GL ;
Black, HR ;
Cushman, WC ;
Green, LA ;
Izzo, JL ;
Jones, DW ;
Materson, BJ ;
Oparil, S ;
Wright, JT ;
Roccella, EJ .
HYPERTENSION, 2003, 42 (06) :1206-1252
[4]  
DEMANCILHACARVA.J, 2003, ARQ BRAS CARDIOL, V80, P289
[5]   Intersalt revisited: Further analyses of 24 hour sodium excretion and blood pressure within and across populations [J].
Elliott, P ;
Stamler, J ;
Nichols, R ;
Dyer, AR ;
Stamler, R ;
Kesteloot, H ;
Marmot, M .
BMJ-BRITISH MEDICAL JOURNAL, 1996, 312 (7041) :1249-1253
[6]  
GUYTON AC, 2004, TXB MED PHYSL, P136
[7]   Effect of salt intake on renal excretion of water in humans [J].
He, FJ ;
Markandu, ND ;
Sagnella, GA ;
MacGregor, GA .
HYPERTENSION, 2001, 38 (03) :317-320
[8]  
KAPLAN NM, 2002, CLIN HYPERTENSION, P23
[9]  
LUTZKY M, 1996, REV MED PUCRS, V6, P24
[10]  
MASSIE BM, 2004, CURRENT MED DIAGNOSI, P118