Modulation of Oxygen-Dependent and Oxygen-Independent Metabolism of Neutrophilic Granulocytes by Quantum Points

被引：2

作者：

Pleskova, S. N. ^{[1
,2
]}

Mikheeva, E. R. ^{[1
,2
]}

机构：

[1] NI Lobachevskii State Univ, Phys Solid State Nanostruct Res & Educ Ctr, Nizhnii Novgorod, Russia

[2] RE Alekseev State Technol Univ, Nizhnii Novgorod, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 151卷 / 04期

基金：

俄罗斯基础研究基金会;

关键词：

quantum points; neutrophilic granulocytes; CYTOTOXICITY; DOTS;

D O I：

10.1007/s10517-011-1359-z

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Inhibition of neutrophilic granulocyte metabolism under the effect of semiconductor quantum points was demonstrated. The status of the oxidative system was evaluated by the NBT test, nonoxidative status by the lysosomal cationic test. It was found that quantum points in a dose of 0.1 mg/ml irrespective of their core and composition of coating significantly inhibited oxygen-dependent and oxygen-independent metabolism of neutrophilic granulocytes.

引用

页码：470 / 472

页数：3

共 7 条

[1]

Gerasimov I G, 2004, Tsitologiia, V46, P155

[2] Probing the cytotoxicity of CdSe quantum dots with surface modification [J].