Practical guidelines for the use of long-acting injectable second-generation antipsychotics

被引：13

作者：

Jarema, Marek ^{[1
]}

Wichniak, Adam ^{[1
]}

Dudek, Dominika ^{[2
]}

Samochowiec, Jerzy ^{[3
]}

Bienkowski, Przemyslaw ^{[4
]}

Rybakowski, Janusz ^{[5
]}

机构：

[1] III Psychiat Clin, Inst Psychiat & Neurol Warsaw, PL-02957 Warsaw, Poland

[2] Jagiellonian Univ, Coll Med, Chair Psychiat, Dept Affect Disorders, PL-31007 Krakow, Poland

[3] Pomeranian Med Univ, Dept Psychiat, Szczecin, Poland

[4] Inst Psychiat & Neurol, Dept Pharmacol, Warsaw, Poland

[5] Poznan Univ Med Sci, Dept Adult Psychiat, Poznan, Poland

来源：

PSYCHIATRIA POLSKA | 2015年 / 49卷 / 02期

关键词：

schizophrenia; long-acting antipsychotics; arpiprazole; olanzapine; paliperidone; risperidone; guidelines for use; DOUBLE-BLIND; SCHIZOPHRENIA; ARIPIPRAZOLE; DRUGS; HOSPITALIZATION; FORMULATIONS; OUTCOMES; DEPOT;

D O I：

10.12740/PP/39370

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Long-acting injectable antipsychotics constitute a valuable alternative for the treatment of psychotic disorders, mainly schizophrenia. They assure a more stable drug level, improve treatment compliance, and increase the chances for favorable and long-lasting improvement. Additionally, the long-acting second-generation antipsychotics combine the values of long-acting injectable drugs with the values of atypical antipsychotics. Four second generation long-acting antipsychotics have been described: risperidone, olanzapine, aripiprazole and paliperidone. The indications for their use, treatment strategy, tolerance, and potential interactions are discussed.

引用

页码：225 / 241

页数：17

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