Real-time monitoring of the mitophagy process by a photostable fluorescent mitochondrion-specific bioprobe with AIE characteristics

被引：106
|
作者：
Zhang, Weijie [1 ,2 ]
Kwok, Ryan T. K. [2 ,3 ]
Chen, Yilong [2 ,3 ]
Chen, Sijie [2 ,3 ]
Zhao, Engui [2 ,3 ]
Yu, Chris Y. Y. [2 ,3 ]
Lam, Jacky W. Y. [2 ,3 ]
Zheng, Qichang [1 ]
Tang, Ben Zhong [2 ,3 ,4 ]
机构：
[1] Huazhong Univ Sci & Technol, Union Hosp, Dept Hepatobiliary Surg, Tongji Med Coll, Wuhan 430022, Peoples R China
[2] Hong Kong Univ Sci & Technol, State Key Lab Mol Neurosci, Div Life Sci,Inst Mol Funct Mat, Dept Chem,Inst Adv Study,Div Biomed Engn, Kowloon, Hong Kong, Peoples R China
[3] HKUST Shenzhen Res Inst, Shenzhen 518057, Peoples R China
[4] S China Univ Technol, State Key Lab Luminescent Mat & Devices, Guangdong Innovat Res Team, SCUT HKUST Joint Res Lab, Guangzhou 510640, Guangdong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 43期
关键词：
AGGREGATION-INDUCED-EMISSION; LIGHT-UP PROBE; QUANTUM DOTS; AUTOPHAGY; DEFENSE;
D O I：
10.1039/c5cc02486b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An isothiocyanate-functionalized tetraphenylethene is synthesized and used as a fluorescent bioprobe for mitochondrion imaging with high specificity and photostability. The covalent conjugation of the bioprobe to mitochondrial proteins endows it with high resistance to microenvironmental changes, enabling it for real-time monitoring of mitophagy.
引用
收藏
页码：9022 / 9025
页数：4
相关论文
共 50 条
  • [21] Real-time process monitoring for changing inputs
    Grimshaw, SD
    Shellman, SD
    Hurwitz, AM
    TECHNOMETRICS, 1998, 40 (04) : 283 - 296
  • [22] A robust strategy for real-time process monitoring
    Doymaz, F
    Chen, J
    Romagnoli, JA
    Palazoglu, A
    JOURNAL OF PROCESS CONTROL, 2001, 11 (04) : 343 - 359
  • [23] REAL-TIME MONITORING OF SEMICONDUCTOR PROCESS UNIFORMITY
    PERLOFF, DS
    HASAN, TF
    BLOME, ER
    SOLID STATE TECHNOLOGY, 1980, 23 (02) : 81 - 86
  • [24] Real-time monitoring of an industrial batch process
    Marjanovic, Ognjen
    Lennox, Barry
    Sandoz, David
    Smith, Keith
    Crofts, Milton
    COMPUTERS & CHEMICAL ENGINEERING, 2006, 30 (10-12) : 1476 - 1481
  • [25] Real-time multivariate process monitoring.
    Domine, D
    Devillers, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211 : 75 - COMP
  • [26] Real-time monitoring viscosity during ferroptosis with a novel mitochondria-specific fluorescent probe
    Zheng, Fan
    Ding, Jipeng
    Huang, Shuai
    Bi, Anyao
    Liu, Shaojun
    Zhang, Kexiang
    Chen, Fei
    Zeng, Wenbin
    DYES AND PIGMENTS, 2023, 217
  • [27] 'AIE plus ESIPT' assisted photorelease: fluorescent organic nanoparticles for dual anticancer drug delivery with real-time monitoring ability
    Biswas, Sandipan
    Mengji, Rakesh
    Barman, Shrabani
    Venugopal, Vangala
    Jana, Avijit
    Singh, N. D. Pradeep
    CHEMICAL COMMUNICATIONS, 2018, 54 (02) : 168 - 171
  • [28] REAL-TIME PROCESS MONITORING IN THE PRODUCTION OF BIOTHERAPEUTICS
    LONDO, T
    VELLA, G
    GORDON, N
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 7 - BTEC
  • [29] Real-time process line monitoring is a winner
    不详
    IIE SOLUTIONS, 2000, 32 (09): : 11 - 11
  • [30] Development of fluorescent tracers for the real-time monitoring of renal function
    Poreddy, Amruta R.
    Asmelash, Bethel
    Debreczeny, Martin P.
    Fitch, Richard M.
    Freskos, John N.
    Galen, Karen P.
    Gaston, Kimberly R.
    Kostelc, James G.
    Kumar, Rana
    Marzan, Tim A.
    Neumann, William L.
    Rajagopalan, Raghavan
    Schoenstein, Tasha M.
    Shieh, Jeng-Jong
    Wilcox, J. Micah
    Wojdyla, Jolette K.
    Dorshow, Richard B.
    REPORTERS, MARKERS, DYES, NANOPARTICLES, AND MOLECULAR PROBES FOR BIOMEDICAL APPLICATIONS III, 2011, 7910
12345