Clarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia

被引：28

作者：

Carella, Angelo Michele ^{[1
]}

Beltrami, Germana ^{[1
]}

Pica, Gianmatteo ^{[1
]}

Carella, Andrea ^{[1
]}

Catania, Gioacchino ^{[1
]}

机构：

[1] IST Ist Nazl Ric Canc, Div Hematol, IRCCS Azienda Osped Univ San Martino, Genoa, Italy

来源：

LEUKEMIA & LYMPHOMA | 2012年 / 53卷 / 07期

关键词：

AUTOPHAGY; CELLS; BIRD;

D O I：

10.3109/10428194.2012.656105

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1409 / 1411

页数：3

共 10 条

[1] Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells [J].

Bellodi, Cristian ;

Lidonnici, Maria Rosa ;

Hamilton, Ashley ;

Helgason, G. Vignir ;

Soliera, Angela Rachele ;

Ronchetti, Mattia ;

Galavotti, Sara ;

Young, Kenneth W. ;

Selmi, Tommaso ;

Yacobi, Rinat ;

Van Etten, Richard A. ;

Donato, Nick ;

Hunter, Ann ;

Dinsdale, David ;

Tirro, Elena ;

Vigneri, Paolo ;

Nicotera, Pierluigi ;

Dyer, Martin J. ;

Holyoake, Tessa ;

Salomoni, Paolo ;

Calabretta, Bruno .

JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (05) :1109-1123

[2] Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors [J].

Calabretta, Bruno ;

Salomoni, Paolo .

LEUKEMIA & LYMPHOMA, 2011, 52 :54-59

[3] Autografting with Philadelphia chromosome-negative mobilized hematopoietic progenitor cells in chronic myelogenous leukemia [J].

Carella, AM ;

Lerma, E ;

Corsetti, MT ;

Dejana, A ;

Basta, P ;

Vassallo, F ;

Abate, M ;

Soracco, M ;

Benvenuto, F ;

Figari, O ;

Podestà, M ;

Piaggio, G ;

Ferrara, R ;

Sessarego, M ;

Parodi, C ;

Pizzuti, M ;

Rubagotti, A ;

Occhini, D ;

Frassoni, F .

BLOOD, 1999, 93 (05) :1534-1539

[4] Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma [J].

Gay, Francesca ;

Rajkumar, S. Vincent ;

Coleman, Morton ;

Kumar, Shaji ;

Mark, Tomer ;

Dispenzieri, Angela ;

Pearse, Roger ;

Gertz, Morie A. ;

Leonard, John ;

Lacy, Martha Q. ;

Chen-Kiang, Selina ;

Roy, Vivek ;

Jayabalan, David S. ;

Lust, John A. ;

Witzig, Thomas E. ;

Fonseca, Rafael ;

Kyle, Robert A. ;

Greipp, Philip R. ;

Stewart, A. Keith ;

Niesvizky, Ruben .

AMERICAN JOURNAL OF HEMATOLOGY, 2010, 85 (09) :664-669

[5] Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML [J].

Helgason, G. Vignir ;

Karvela, Maria ;

Holyoake, Tessa L. .

BLOOD, 2011, 118 (08) :2035-2043

[6] mTOR regulation of autophagy [J].

Jung, Chang Hwa ;

Ro, Seung-Hyun ;

Cao, Jing ;

Otto, Neil Michael ;

Kim, Do-Hyung .

FEBS LETTERS, 2010, 584 (07) :1287-1295

[7] Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs [J].

Mohi, MG ;

Boulton, C ;

Gu, TL ;

Sternberg, DW ;

Neuberg, D ;

Griffin, JD ;

Gilliland, DG ;

Neel, BG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (09) :3130-3135

[8] Clarithromycin with low dose dexamethasone and thalidomide is effective therapy in relapsed/refractory myeloma [J].

Morris, T. C. M. ;

Kettle, P. J. ;

Drake, M. ;

Jones, F. C. G. ;

Hull, D. R. ;

Boyd, K. ;

Morrison, A. ;

Clarke, P. ;

O'Reilly, P. ;

Quinn, J. .

BRITISH JOURNAL OF HAEMATOLOGY, 2008, 143 (03) :349-354

[9] Clarithromycin attenuates autophagy in myeloma cells [J].

Nakamura, Miki ;

Kikukawa, Yoshitaka ;

Takeya, Motohiro ;

Mitsuya, Hiroaki ;

Hata, Hiroyuki .

INTERNATIONAL JOURNAL OF ONCOLOGY, 2010, 37 (04) :815-820

[10] Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene [J].

Qu, XP ;

Yu, J ;

Bhagat, G ;

Furuya, N ;

Hibshoosh, H ;

Troxel, A ;

Rosen, J ;

Eskelinen, EL ;

Mizushima, N ;

Ohsumi, Y ;

Cattoretti, G ;

Levine, B .

JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (12) :1809-1820

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