Male reproductive toxicity of organophosphorous compounds: a review

被引：21

作者：

Joshi, Suresh C. ^{[1
]}

Sharma, Preeti ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Zool, Ctr Adv Studies, Reprod Toxicol Unit, Jaipur 302055, Rajasthan, India

来源：

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY | 2011年 / 93卷 / 07期

关键词：

organophosphorous compounds; reproductive toxicity; insecticides; fertility; exposure; TESTICULAR DYSGENESIS SYNDROME; NEUROPATHY TARGET ESTERASE; METHYL PARATHION EXPOSURE; MALE RATS; 2,4-DICHLOROPHENOXYACETIC ACID; CHLORPYRIFOS TOXICITY; PIRIMIPHOS-METHYL; SPERM COUNTS; MALE-MICE; IN-VITRO;

D O I：

10.1080/02772248.2011.581874

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Fertility is declining in many countries and there has been substantial interest in the potential adverse effects of exposure to environmental hazardous chemicals, including pesticides on male reproduction. Organophosphorous compounds (organophosphates, OP) constitute a heterogeneous category of chemicals specifically designed for the control of pests or plant diseases. OP are known to produce reproductive toxicity, resulting in a decrease in the fertility levels of humans and animals. This review article mainly focused on toxicity of some OP such as acephate, chlorpyrifos, diazinon, dimethoate, fenitrothion, malathion, and monocrotophos especially dealing with reproductive toxicity in males. Furthermore, this review deals with mode of action and clinical syndromes of OP. Considerable lab studies on animals concluded that OP produce adverse effects on male reproductive system.

引用

页码：1486 / 1507

页数：22

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