Exploratory eye movement dysfunctions in patients with schizophrenia: possibility as a discriminator for schizophrenia

被引:40
作者
Matsushima, E
Kojima, T
Ohta, K
Obayashi, S
Nakajima, K
Kakuma, T
Ando, H
Ando, K
Toru, M
机构
[1] Tokyo Med & Dent Univ, Sch Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138519, Japan
[2] Nihon Univ, Dept Neuropsychiat, Tokyo, Japan
[3] Cornell Univ, Med Ctr, New York Hosp, New York, NY 10021 USA
关键词
D O I
10.1016/S0022-3956(98)00019-3
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
In our previous studies patients with schizophrenia and their parents had less frequent eye fixations and a more limited area of inspection than normal controls while freely viewing stationary S-shaped figures. The present study attempted to discriminate schizophrenics from non-schizophrenics using exploratory eye movements. Two groups (A and B) were formed, each comprising 30 schizophrenic and 70 non-schizophrenic subjects (10 each of patients with depression, methamphetamine psychosis, alcohol psychosis, anxiety disorder, temporal lobe epilepsy, frontal lobe lesions and healthy normal controls). Discriminant analysis was performed on group A to obtain a discriminant. The validity of applying this discriminant to group B was investigated. By focussing on exploratory eye movements, schizophrenics could be discriminated from non-schizophrenics with a sensitivity of 76.7% and a specificity of 81.4%. These results show that exploratory eye movements are a useful discriminator for schizophrenia. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:289 / 295
页数:7
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