Synthesis of Amides via Palladium-Catalyzed Amidation of Aryl Halides

被引：171

作者：

Jiang, Huanfeng ^{[1
]}

Liu, Bifu ^{[1
]}

Li, Yibiao ^{[1
]}

Wang, Azhong ^{[1
]}

Huang, Huawen ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 05期

基金：

中国国家自然科学基金;

关键词：

PD-C BOND; CARBON-MONOXIDE; CARBONYLATION REACTIONS; ATMOSPHERIC-PRESSURE; GENERAL-SOLUTION; AMINO-ACIDS; ALCOHOLS; AMINOCARBONYLATION; COMPLEXES; EFFICIENT;

D O I：

10.1021/ol103081y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and efficient method for the synthesis of amides via palladium-catalyzed C-C coupling of aryl halides with isocyanides is reported, by which a series of amides were formed from readily available starting materials under mild conditions. This transformation could extend its use to the synthesis of natural products and significant pharmaceuticals.

引用

页码：1028 / 1031

页数：4

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