Biomedical implications of information processing in chemical systems: Non-classical approach to photochemistry of coordination compounds

被引:5
作者
Szacilowski, Konrad [1 ]
机构
[1] Jagiellonian Univ, Fac Chem, Ctr Inorganic Nanochem, PL-30060 Krakow, Poland
关键词
molecular logic gates; operation amplifiers; nitric oxide; photochemistry;
D O I
10.1016/j.biosystems.2007.03.002
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Analogies between photoactive nitric oxide generators and various electronic devices: logic gates and operational amplifiers are presented. These analogies have important biological consequences: application of control parameters allows for better targeting and control of nitric oxide drugs. The same methodology may be applied in the future for other therapeutic strategies and at the same time helps to understand natural regulatory and signaling processes in biological systems. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:738 / 749
页数:12
相关论文
共 95 条
  • [1] Adams DR, 1999, PROG CH ORG NAT PROD, V76, P1
  • [2] Photosensitizers in clinical PDT
    Allison, Ron R.
    Downie, Gordon H.
    Cuenca, Rosa
    Hu, Xin-Hua
    Childs, Carter J. H.
    Sibata, Claudio H.
    [J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2004, 1 (01) : 27 - 42
  • [3] Prodrug activation gated by a molecular "OR" logic trigger
    Amir, RJ
    Popkov, M
    Lerner, RA
    Barbas, CF
    Shabat, D
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (28) : 4378 - 4381
  • [4] New directions in incidence-dose modeling
    Andersen, ME
    Dennison, JE
    Thomas, RS
    Conolly, RB
    [J]. TRENDS IN BIOTECHNOLOGY, 2005, 23 (03) : 122 - 127
  • [5] INHIBITION OF CLOSTRIDIUM-PERFRINGENS BY HEATED COMBINATIONS OF NITRITE, SULFUR, AND FERROUS OR FERRIC IONS
    ASAN, T
    SOLBERG, M
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1976, 31 (01) : 49 - 52
  • [6] MOLECULAR RECTIFIERS
    AVIRAM, A
    RATNER, MA
    [J]. CHEMICAL PHYSICS LETTERS, 1974, 29 (02) : 277 - 283
  • [7] Balzani V., 2003, Molecular Devices and Machines, a Journey into the Nanoworld
  • [8] BESTANE WJ, 2001, BRAZ J UROL, V27, P155
  • [9] Nitric oxide, cell signaling and cell death
    Blaise, GA
    Gauvin, D
    Gangal, M
    Authier, S
    [J]. TOXICOLOGY, 2005, 208 (02) : 177 - 192
  • [10] BONNETT R, 2000, CHEMICAL ASPECTS PHO