Thermally Stable Honeycomb-Patterned Porous Films of a Poly(L-lactic acid) and Poly(D-lactic acid) Stereo Complex Prepared Using the Breath Figure Technique

被引:10
作者
Abe, Hiroya [1 ]
Hirai, Yutaro [1 ]
Yabu, Hiroshi [1 ]
机构
[1] Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan
基金
日本学术振兴会;
关键词
breath figure; honeycomb film; poly(lactic acid); self-organization; stereo complex; SELF-ORGANIZED HONEYCOMB; TISSUE ENGINEERING SCAFFOLDS; STEREOCOMPLEX FORMATION; BIOMEDICAL APPLICATIONS; SURFACE-TOPOGRAPHY; POLYMER-FILM; CELL-GROWTH; PORE-SIZE; IN-VITRO; ADHESION;
D O I
10.1002/mame.201500474
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Porous polymer materials prepared from biodegradable polymers have received considerable attention due to their potential as cell culture scaffolds for tissue engineering. Porous materials are generally sterilized by autoclaving prior to use as cell culture scaffolds to avoid unexpected biological infection. However, the melting point of biodegradable polymers is typically lower than the temperature used in autoclave sterilization. Here, the preparation of honeycomb films comprising a poly(L-lactic acid) (PLLA) and poly(D-lactic acid) (PDLA) stereo complex is described and their thermal stabilities are evaluated. The hierarchic photochemical patterning of PLLA/PDLA stereo complex honeycomb-patterned films by UV-O-3 treatment is also demonstrated.
引用
收藏
页码:523 / 529
页数:7
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