Thymoma With Nuclear Expression of Thyroid Transcription Factor-1 A Potential Diagnostic Pitfall on Core Biopsy

被引：4

作者：

Yan, Benedict ^{[1
]}

Seng, Sim Chee ^{[2
]}

Petersson, Fredrik ^{[1
]}

机构：

[1] Natl Univ Hosp Syst, Dept Pathol, Singapore, Singapore

[2] Parkway Lab Serv, Singapore, Singapore

来源：

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY | 2011年 / 19卷 / 01期

关键词：

thymoma; thyroid transcription factor-1; TTF-1; T-CELL TOLERANCE; SELF-ANTIGEN POOLS; THYMIC CARCINOMA; NEUROENDOCRINE DIFFERENTIATION; MONOCLONAL-ANTIBODIES; EPITHELIAL NEOPLASMS; ATYPICAL THYMOMA; GENES; MECHANISMS; PULMONARY;

D O I：

10.1097/PAI.0b013e3181ec8a50

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The clinicopathologic features of the first case of a thymoma with a strong nuclear expression of thyroid transcription factor-1 are reported. The thymoma was classified as type AB according to the WHO-system. No definitive correlation between the different histologic patterns or neoplastic cell types and thyroid transcription factor-1 expression was discerned. No immunohistochemical evidence of neuroendocrine differentiation was identified with synaptophysin, chromogranin A, and CD56.

引用

页码：76 / 81

页数：6

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