Acyl moiety and temperature affects thermo-oxidative degradation of steryl esters. Cytotoxicity of the degradation products

被引：15
作者：
Kasprzak, Maria [1 ]
Rudzinska, Magdalena [1 ]
Kmiecik, Dominik [1 ]
Przybylski, Roman [2 ]
Olejnik, Anna [1 ]
机构：
[1] Poznan Univ Life Sci, Fac Food Sci & Nutr, Wojska Polskiego 28, PL-60637 Poznan, Poland
[2] Univ Lethbridge, Dept Chem & Biochem, 4401 Univ Dr W, Lethbridge, AB T1K 3M4, Canada
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2020年 / 136卷
关键词：
Phytosterol esters; Storage; Heating; Degradation; Oxyphytosterols; Oligomerization; Cytotoxicity; PHYTOSTEROL OXIDATION-PRODUCTS; PLANT STEROLS; SITOSTEROL; OILS; MARGARINES; STABILITY; RAPESEED; PLASMA; FOODS;
D O I：
10.1016/j.fct.2019.111074
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Phytosterols and their esters are often used as functional ingredients in food products due to its lowering blood cholesterol properties. Products containing phytosterols and its esters are recommended for direct consumption, cooking, baking and frying, however during food preparation it is possible thermo-oxidative degradation is possible. Unsaturation of fatty acid present in steryl ester may further stimulates degradation. Free stigmasterol degraded faster than its esters, even with linoleic acid attached. The highest amount of degradation products was observed for free stigmasterol, followed by esters with linoleic and oleic acids. Polar dimers were fund in all heated samples, although for free stigmasterol heated at 60 degrees C were not detected. Whereas non-polar dimers were observed only in heated stigmasterol. Degradation of esterified stigmasterol generated degradation products with lower cytotoxicity.
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页数：7
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共 38 条
  • [1] Performance of palm olein and modified rapeseed, sunflower, and soybean oils in intermittent deep-frying
    Aladedunye, Felix
    Przybylski, Roman
    [J]. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2014, 116 (02) : 144 - 152
  • [2] Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells
    Alemany, L.
    Laparra, J. M.
    Barbera, R.
    Alegria, A.
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2013, 56 : 247 - 253
  • [3] [Anonymous], 2010, GLOBAL IND ANAL MARK
  • [4] [Anonymous], 2007, LK07 AOCS, P1
  • [5] Phytosterols reduce in vitro metastatic ability of MDA-MB-231 human breast cancer cells
    Awad, AB
    Williams, H
    Fink, CS
    [J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2001, 40 (02): : 157 - 164
  • [6] Unsaturated lipid matrices protect plant sterols from degradation during heating treatment
    Barriuso, Blanca
    Astiasaran, Iciar
    Ansorena, Diana
    [J]. FOOD CHEMISTRY, 2016, 196 : 451 - 458
  • [7] Sterols heating: Degradation and formation of their ring-structure polar oxidation products
    Barriuso, Blanca
    Otaegui-Arrazola, Ane
    Menendez-Carreno, Maria
    Astiasaran, Iciar
    Ansorena, Diana
    [J]. FOOD CHEMISTRY, 2012, 135 (02) : 706 - 712
  • [8] Postprandial plasma oxyphytosterol concentrations after consumption of plant sterol or stanol enriched mixed meals in healthy subjects
    Baumgartner, Sabine
    Mensink, Ronald P.
    Konings, Maurice
    Schoett, Hans-F.
    Friedrichs, Silvia
    Husche, Constanze
    Luetjohann, Dieter
    Plat, Jogchum
    [J]. STEROIDS, 2015, 99 : 281 - 286
  • [9] Oxidative stability of functional phytosterol-enriched dark chocolate
    Botelho, Patricia Borges
    Galasso, Melissa
    Dias, Virginia
    Mandrioli, Mara
    Lobato, Luciana Pereira
    Rodriguez-Estrada, Maria Teresa
    Castro, Inar Alves
    [J]. LWT-FOOD SCIENCE AND TECHNOLOGY, 2014, 55 (02) : 444 - 451
  • [10] Dobarganes M. C., 2006, Deep frying: chemistry, nutrition, and practical applications, P87
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