Subtraction Magnetocardiogram for Detecting Coronary Heart Disease

被引：11

作者：

Kandori, Akihiko ^{[1
]}

Ogata, Kuniomi ^{[1
]}

Miyashita, Tsuyoshi ^{[1
]}

Takaki, Hiroshi ^{[2
]}

Kanzaki, Hideyuki ^{[2
]}

Hashimoto, Syuji ^{[2
]}

Shimizu, Wataru ^{[2
]}

Kamakura, Shiro ^{[2
]}

Watanabe, Shigeyuki ^{[3
]}

Aonuma, Kazutaka ^{[3
]}

机构：

[1] Hitachi Ltd, Adv Res Lab, Tokyo 1858601, Japan

[2] Natl Cardiovasc Ctr, Osaka, Japan

[3] Univ Tsukuba, Tsukuba, Ibaraki 305, Japan

来源：

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY | 2010年 / 15卷 / 04期

关键词：

magnetocardiogram; subtraction; current-arrow map; Coronary Heart Disease; MYOCARDIAL ABNORMALITY; ARTERY-DISEASE; ISCHEMIA; ECG;

D O I：

10.1111/j.1542-474X.2010.00392.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Methods: We used MCGs of 56 CHD patients (63 +/- 3 years old) and 101 age-matched normal control patients (65 +/- 5 years old). To construct a subtracted ST-T waveform, we used standard MCG waveforms produced from 464 normal MCGs (male: 268, female: 196). The standard MCG waveforms were subtracted from each subject's measured MCGs, which were shortened or lengthened and normalized to adjust to the data length and magnitude of the standard waveform. We evaluated the maximum amplitude and maximum current-arrow magnitude of the subtracted ST-T waveform. Results: The maximum magnetic field, maximum magnitude of current arrows, and maximum magnitude of total current vector increased according to the number of coronary artery lesions. The sensitivity and specificity of detecting CHD and normal control patients were 74.6% and 84.1%, respectively. Conclusions: The subtraction MCG method can be used to detect CHD with high accuracy, namely, sensitivity of 74.6% and specificity of 84.1% (in the case of maximum amplitude of total current vector). Furthermore, the subtraction MCG magnitude and its current distribution can reflect the expanse of the ischemic lesion area and the progress from ischemia to myocardial infarction. Ann Noninvasive Electrocardiol 2010;15(4):360-368.

引用

页码：360 / 368

页数：9

共 22 条

[1] Noninvasive coronary artery Imaging - Magnetic resonance angiography and multidetector computed tomography angiography - A scientific statement from the American Heart Association Committee on cardiovascular imaging and intervention of the council on cardiovascular radiology and intervention, and the councils on clinical cardiology and cardiovascular disease in the young [J].