Successful treatment of hemorrhagic bullous Henoch-Schonlein purpura with intravenous immunoglobulins

被引：14

作者：

Mauro, Angela ^{[1
]}

Mauro, Salvatore ^{[1
]}

Rega, Roberto ^{[2
]}

Martemucci, Luigi ^{[2
]}

Sottile, Rita ^{[2
]}

机构：

[1] Santa Maria Pieta Hosp, Dept Paediat, Nola Naples, Italy

[2] Santobono Pausilipon Childrens Hosp, Dept Paediat, Naples, Italy

来源：

PEDIATRIC DERMATOLOGY | 2019年 / 36卷 / 01期

关键词：

hemorrhagic bullous; Henoch-Schonlein purpura; intravenous immunoglobulin; treatment; THERAPY;

D O I：

10.1111/pde.13715

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Henoch-Schonlein purpura (HSP) is the most common systemic vasculitis in childhood. There is no consensus about the management for isolated cutaneous manifestations in HSP. We describe a case of HSP presenting with severe skin lesions that did not respond to standard therapy with corticosteroids. The 11-year-old child was treated with intravenous immunoglobulins, which induced rapid and persistent resolution of symptomatology.

引用

页码：E34 / E36

页数：3

共 15 条

[1] Intravenous immunoglobulins for severe gastrointestinal involvement in pediatric Henoch-Schonlein gurpura: A French retrospective study [J].

Cherqaoui, B. ;

Chausset, A. ;

Stephan, J. -L. ;

Merlin, E. .

ARCHIVES DE PEDIATRIE, 2016, 23 (06) :584-590

[2] Intravenous immunoglobulin in Henoch-Schonlein purpura complicated by cerebral hemorrhage [J].

De Maddi, Francesco ;

Dinardo, Rocco ;

Buonocore, Maria Consiglio ;

Dinardo, Michele ;

Bartolomei, Beatrice ;

Rigante, Donato .

RHEUMATOLOGY INTERNATIONAL, 2013, 33 (09) :2451-2453

[3] Bullous lesions in Henoch Schonlein Purpura as indication to start systemic prednisone [J].

den Boer, S. L. ;

Pasmans, S. G. M. A. ;

Wulffraat, N. M. ;

Ramakers-Van Woerden, N. L. ;

Bousema, M. T. .

ACTA PAEDIATRICA, 2010, 99 (05) :781-783

[4]

Dhanjal Sacha, 2017, BMJ Case Rep, V2017, DOI 10.1136/bcr-2016-218903

[5] Vasculitis in children [J].

Eleftheriou, Despina ;

Batu, Ezgi Deniz ;

Ozen, Seza ;

Brogan, Paul A. .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2015, 30 :i94-i103

[6] Massive gastrointestinal haemorrhage in isolated intestinal Henoch-Schonlein purpura with response to intravenous immunoglobulin infusion [J].

Fagbemi, Andrew A. O. ;

Torrente, Franco ;

Hilson, Andrew J. W. ;

Thomson, Michael A. ;

Heuschkel, Robert B. ;

Murch, Simon H. .

EUROPEAN JOURNAL OF PEDIATRICS, 2007, 166 (09) :915-919

[7] Azathioprine therapy for steroid-resistant Henoch-Schonlein purpura: a report of 6 cases [J].

Fotis, Lampros ;

Tuttle, Paul V. ;

Baszis, Kevin W. ;

Pepmueller, Peri H. ;

Moore, Terry L. ;

White, Andrew J. .

PEDIATRIC RHEUMATOLOGY, 2016, 14

[8] Pediatric Henoch-Schonlein purpura [J].

Gonzalez, Lenis M. ;

Janniger, Camila Krysicka ;

Schwartz, Robert A. .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2009, 48 (11) :1157-1165

[9] Dapsone therapy for Henoch-Schonlein purpura: a case series [J].

Iqbal, H ;

Evans, A .

ARCHIVES OF DISEASE IN CHILDHOOD, 2005, 90 (09) :985-986

[10] Late Intravenous Immunoglobulin Treatment in Patients With Kawasaki Disease [J].

Muta, Hiromi ;

Ishii, Masahiro ;

Yashiro, Mayumi ;

Uehara, Ritei ;

Nakamura, Yosikazu .

PEDIATRICS, 2012, 129 (02) :E291-E297

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