共 138 条
Colloidal micelles of block copolymers as nanoreactors, templates for gold nanoparticles, and vehicles for biomedical applications
被引:49
作者:

Bakshi, Mandeep Singh
论文数: 0 引用数: 0
h-index: 0
机构:
Wilfrid Laurier Univ, Dept Chem, Waterloo, ON N2L 3C5, Canada Wilfrid Laurier Univ, Dept Chem, Waterloo, ON N2L 3C5, Canada
机构:
[1] Wilfrid Laurier Univ, Dept Chem, Waterloo, ON N2L 3C5, Canada
关键词:
Block copolymer micelles;
Gold nanoparticles;
Nanoreactors;
Biomedical applications;
TRIBLOCK COPOLYMER;
POLYMERIC MICELLES;
IONIC SURFACTANTS;
MIXED MICELLES;
INORGANIC NANOPARTICLES;
MULTIPLE MORPHOLOGIES;
CATALYTIC-PROPERTIES;
RADIATION-THERAPY;
METHYL-ORANGE;
PLURONIC F127;
D O I:
10.1016/j.cis.2014.08.001
中图分类号:
O64 [物理化学(理论化学)、化学物理学];
学科分类号:
070304 ;
081704 ;
摘要:
Target drug delivery methodology is becoming increasingly important to overcome the shortcomings of conventional drug delivery absorption method. It improves the action time with uniform distribution and poses minimum side effects, but is usually difficult to design to achieve the desire results. Economically favorable, environment friendly, multifunctional, and easy to design, hybrid nanomaterials have demonstrated their enormous potential as target drug delivery vehicles. A combination of both micelles and nanoparticles makes them fine target delivery vehicles in a variety of biological applications where precision is primarily required to achieve the desired results as in the case of cytotoxicity of cancer cells, chemotherapy, and computed tomography guided radiation therapy. (C) 2014 Elsevier B.V. All rights reserved.
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页数:20
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