High prevalence of diverse vancomycin resistance Enterococcus faecium isolates in clinical and environmental sources in ICU wards in southwest of Iran

被引：8
作者：
Arshadi, Maniya [1 ]
Douraghi, Masoumeh [1 ]
Shokoohizadeh, Leili [2 ]
Moosavian, Seyed Mojtaba [3 ]
Pourmand, Mohammad Reza [1 ]
机构：
[1] Univ Tehran Med Sci, Sch Publ Hlth, Dept Pathobiol, Tehran, Iran
[2] Hamedan Univ Med Sci, Dept Microbiol, Fac Med, Hamadan, Iran
[3] Ahvaz Jundishapur Univ Med Sci, Hlth Res Inst, Infect & Trop Dis Res Ctr, Ahvaz, Iran
来源：
MICROBIAL PATHOGENESIS | 2017年 / 111卷
关键词：
Enterococcus faecium; PFGE; VRE; Different source; MULTIPLEX PCR; VIRULENCE; CONTAMINATION; COLONIZATION; TRANSMISSION; ACQUISITION; EPIDEMIOLOGY; SURVEILLANCE; INFECTIONS; BACTEREMIA;
D O I：
10.1016/j.micpath.2017.08.045
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This study aimed at determining the prevalence, antibiotic resistance patterns, and genetic linkage of Vancomycin Resistant Enterococcus faecium (VREfm) from different sources in the southwest of Iran. A total of 51 VREfm isolates were obtained and subjected to antibiotic susceptibility testing, carriage of virulence genes, and pulsed-field gel electrophoresis (PFGE) method. All the VRE isolates exhibited a high level of resistance to teicoplanin, ampicillin, erythromycin, ciprofloxacin, and gentamicin, also carried the vanA gene. A total of 59% and 34% of the VREfm strains harbored esp and hyl genes, respectively. The results from PFGE showed 31 PFGE patterns including 10 common types (CT) and 21 single types (ST) among the VRE isolates. Furthermore, isolates from different sources in each common type revealed cross transmission between clinical and environmental sources. Overall, the study showed a high prevalence of diverse VRE faecium strains with threatening resistance phenotypes in the environment and clinical sections among different ICU wards of Ahvaz hospitals. (C) 2017 Elsevier Ltd. All rights reserved.
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收藏
页码：212 / 217
页数：6
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