Indolylmethanols as Reactants in Catalytic Asymmetric Reactions

被引：149

作者：

Mei, Guang-Jian ^{[1
]}

Shi, Feng ^{[1
]}

机构：

[1] Jiangsu Normal Univ, Sch Chem & Mat Sci, Xuzhou 221116, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 15期

基金：

中国国家自然科学基金;

关键词：

BRONSTED-ACID CATALYSIS; TETRAHYDRO-BETA-CARBOLINE; FRIEDEL-CRAFTS REACTION; DIELS-ALDER REACTION; ENANTIOSELECTIVE SYNTHESIS; PHOSPHORIC-ACID; ALPHA-ALKYLATION; FLUORENE DERIVATIVES; INDOL-2-YL CARBINOLS; INDOLE-DERIVATIVES;

D O I：

10.1021/acs.joc.7b01458

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indolylmethanols have emerged as versatile reactants in catalytic asymmetric reactions because of the facile generation of reactive intermediates from these compounds. The most common indolylmethanols are 3-indolylmethanols and 2-indolylmethanols, and the reaction types applicable to these heterocycles mainly include catalytic enantioselective substitutions and cyclizations. Using indolylmethanols as reactants in catalytic asymmetric reactions enables the enantioselective construction of a variety of indole-containing frameworks.

引用

页码：7695 / 7707

页数：13

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