The effects of exposure to extremely low-frequency magnetic field and amphetamine on the reduced glutathione in the brain

被引:7
|
作者
Jelenkovic, A
Janac, B
Pesic, V
Jovanovic, MD
Vasiljevic, I
Prolic, Z
机构
[1] Inst Biol Res Dr Sinisa Stankovic, Belgrade, Serbia Monteneg
[2] Mil Med Acad, Inst Med Res, Belgrade, Serbia Monteneg
关键词
ELF-MF; reduced glutathione; amphetamine;
D O I
10.1196/annals.1342.044
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Continuous exposure to extremely low-frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) alone and combined with D-amphetamine (1.5 mg/kg) affected the reduced glutathione content in brain regions of rats. Compared to sham-exposed rats, the glutathione content in the forebrain cortex of the ELFMF-exposed rats decreased (P < 0.001), but this reverted after giving amphetamine upon ELF-MF exposure. In this group, the glutathione content was increased in the brain stem and cerebellum (P < 0.05 compared to the shame-exposed, ELM-MF-exposed, and amphetamine-treated groups). It is suggested that biogenic monoamines are involved in the reduced glutathione changes observed. The changes are not uniform in the brain regions examined.
引用
收藏
页码:377 / 380
页数:4
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