Iridium-catalyzed enantioselective hydrogenation of α,β-unsaturated carboxylic acids

被引：132

作者：

Li, Shen ^{[1
]}

Zhu, Shou-Fei ^{[1
]}

Zhang, Can-Ming ^{[1
]}

Song, Song ^{[1
]}

Zhou, Qi-Lin ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 27期

关键词：

D O I：

10.1021/ja802399v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly efficient iridium-catalyzed hydrogenation of alpha,beta-unsaturated carboxylic acids has been developed by using chiral spiro-phosphino-oxazoline ligands, affording a-substituted chiral carboxylic acids in exceptionally high enantioselectivities and reactivities.

引用

页码：8584 / +

页数：3

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