An Outbreak of Salmonella Serotype Typhimurium Infections with an Unusually Long Incubation Period

被引：14

作者：

Brooks, John T. ^{[1
,3
]}

Matyas, Bela T. ^{[4
]}

Fontana, John ^{[4
]}

DeGroot, Mary Ann ^{[5
]}

Beuchat, Larry R. ^{[6
]}

Hoekstra, Michael ^{[2
]}

Friedman, Cindy R. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Foodborne & Diarrheal Dis Branch, Atlanta, GA USA

[2] Ctr Dis Control & Prevent, Biostat & Informat Management Branch, Div Bacterial & Mycot Dis, Natl Ctr Infect Dis, Atlanta, GA USA

[3] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Epidemiol Program Off, Atlanta, GA USA

[4] Massachusetts Dept Hlth, Boston, MA USA

[5] Colorado State Univ, Dept Microbiol Immunol & Pathol, Ft Collins, CO 80523 USA

[6] Univ Georgia, Ctr Food Safety, Griffin, GA USA

来源：

FOODBORNE PATHOGENS AND DISEASE | 2012年 / 9卷 / 03期

关键词：

RAW-MILK; VIRULENCE GENES; DISEASE; ASSOCIATION; RESISTANT; PLASMID;

D O I：

10.1089/fpd.2011.0992

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

A 1998 investigation of an outbreak of Salmonella serotype Typhimurium infections among children tasting unpasteurized milk during tours of a dairy farm demonstrated a distribution of unusually long incubation periods (median, 8 days; interquartile range [IQR], 6-14 days). Bacterial isolates were highly acid tolerant and contained genes associated with protection against destructive phagocytic reactive oxygen intermediates. We hypothesize that exposure to low-dose oral inoculum of a pathogen with these properties could have contributed to cases of non-typhoidal salmonellosis with the longest incubation period reported to the Centers for Disease Control and Prevention (CDC).

引用

页码：245 / 248

页数：4

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