Rhenium-catalyzed synthesis of multisubstituted aromatic compounds via C-C single-bond cleavage

被引：67

作者：

Kuninobu, Yoichiro ^{[1
]}

Takata, Hisatsugu ^{[1
]}

Kawata, Atsushi ^{[1
]}

Takai, Kazuhiko ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Nat Sci & Technol, Div Chem & Biochem, Okayama 7008530, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 14期

关键词：

D O I：

10.1021/ol801226t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A reaction between a beta-keto ester and an acetylene in the presence of a rhenium complex, [ReBr(CO)(3)(thf)](2), as a catalyst, provided a 2-pyranone derivative in excellent yield via retro-aldol reaction (C-C single bond cleavage). By adding an acetylene-bearing ester group(s) after the formation of 2-pyranones, an aromatization reaction proceeded and multisubstituted aromatic compounds were obtained in good to excellent yields.

引用

页码：3133 / 3135

页数：3

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