Spatial fragment distribution from a therapeutic pencil-like carbon beam in water

被引:72
作者
Matsufuji, N [1 ]
Komori, M
Sasaki, H
Akiu, K
Ogawa, M
Fukumura, A
Urakabe, E
Inaniwa, T
Nishio, T
Kohno, T
Kanai, T
机构
[1] Natl Inst Radiol Sci, Res Ctr Charged Particle Theory, Chiba 2638555, Japan
[2] Tokyo Inst Technol, Dept Energy Sci, Yokohama, Kanagawa 2268502, Japan
[3] Natl Canc Ctr, E Hosp, Kashiwa, Chiba 2778577, Japan
关键词
D O I
10.1088/0031-9155/50/14/014
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The latest heavy ion therapy tends to require information about the spatial distribution of the quality of radiation in a patient's body in order to make the best use of any potential advantage of swift heavy ions for the therapeutic treatment of a tumour. The deflection of incident particles is described well by Moliere's multiple-scattering theory of primary particles; however, the deflection of projectile fragments is not yet thoroughly understood. This paper reports on our investigation of the spatial distribution of fragments produced from a therapeutic carbon beam through nuclear reactions in thick water. A Delta E-E counter telescope system, composed of a plastic scintillator, a gasflow proportional counter and a BGO scintillator, was rotated around a water target in order to measure the spatial distribution of the radiation quality. The results revealed that the observed deflection of fragment particles exceeded the multiple scattering effect estimated by Moliere's theory. However, the difference can be sufficiently accounted for by considering one term involved in the multiple-scattering formula; this term corresponds to a lateral 'kick' at the point of production of the fragment. This kick is successfully explained as a transfer of the intra-nucleus Fermi momentum of a projectile to the fragment; the extent of the kick obeys the expectation derived from the Goldhaber model.
引用
收藏
页码:3393 / 3403
页数:11
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