Chromones and coumarins from the dried fructus of Cnidium monnieri

被引：42

作者：

Zhao, Jianyu ^{[1
,2
]}

Zhou, Min ^{[1
]}

Liu, Yan ^{[1
]}

Zhang, Guolin ^{[1
]}

Luo, Yinggang ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Biol, Ctr Nat Prod Res, Chengdu 610041, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing, Peoples R China

来源：

FITOTERAPIA | 2011年 / 82卷 / 05期

关键词：

Cnidium monnieri; Chromone; Coumarin; Hydroxycnidimoside A; Hydroxyosthole epoxide; MURRAYA-EXOTICA; DOUBLE-BONDS; CONFIGURATION; CONSTITUENTS; TERPENOIDS; AURAPTENOL;

D O I：

10.1016/j.fitote.2011.03.008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Chemical investigations on the ethanolic extract of the dried fructus of Cnidium monnieri offered three chromones and eight coumarins. Among them, a new chromone and a new coumarin were identified and elucidated as 5,7-dihydroxy-6-[(2Z)-4-(beta-D-glucopyranosyl) oxy-3- methylbut-2-enyl]-2-hydroxymethyl-4H-1-benzopyran-4-one (1, hydroxycnidimoside A) and (ref 1'S,2'R)-8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin (8, hydroxyosthole epoxide), respectively, by extensive analyses of spectroscopic data including 1- and 2-D NMR, MS, UV. OR, IR. and HRMS data. The other known compounds were identified by analyses of spectroscopic data and by comparison with literature reported. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：767 / 771

页数：5

共 28 条

[1] CHROMONES FROM CNIDIUM-MONNIERI [J].

BABA, K ;

KAWANISHI, H ;

TANIGUCHI, M ;

KOZAWA, M .

PHYTOCHEMISTRY, 1992, 31 (04) :1367-1370

[2] COUMARINS OF MURRAYA-EXOTICA - ABSOLUTE-CONFIGURATION OF AURAPTENOL [J].

BARIK, BR ;

DEY, AK ;

DAS, PC ;

CHATTERJEE, A ;

SHOOLERY, JN .

PHYTOCHEMISTRY, 1983, 22 (03) :792-794

[3] STEREOCHEMISTRY OF TRISUBSTITUTED DOUBLE BONDS IN TERPENOIDS [J].

BATES, RB ;

GALE, DM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1960, 82 (21) :5749-5751

[4] Coumarins from the fruits of Cnidium monnieri [J].

Cai, JN ;

Basnet, P ;

Wang, ZT ;

Komatsu, K ;

Xu, LS ;

Tani, T .

JOURNAL OF NATURAL PRODUCTS, 2000, 63 (04) :485-488

[5] COUMARINS AND ANTIPLATETLET AGGREGATION CONSTITUENTS FROM ZANTHOXYLUM-SCHINIFOLIUM [J].

CHEN, IS ;

LIN, YC ;

TSAI, IL ;

TENG, CM ;

KO, FN ;

ISHIKAWA, T ;

ISHII, H .

PHYTOCHEMISTRY, 1995, 39 (05) :1091-1097

[6]

[陈艳 CHEN Yan], 2006, [沈阳药科大学学报, Journal of Shenyang Pharmaceutical University], V23, P256

[7]

Chinese Pharmacopoeia Commission, 2010, PHARM PEOPL REP CHIN, V1, P295

[8]

GANTIMUR D, 1981, Chemistry of Natural Compounds (English Translation of Khimiya Prirodnykh Soedinenii), V17, P41, DOI 10.1007/BF00566431

[9] STEROIDS, CHROMONE AND COUMARINS FROM ANGELICA-OFFICINALIS [J].

HARKAR, S ;

RAZDAN, TK ;

WAIGHT, ES .

PHYTOCHEMISTRY, 1984, 23 (02) :419-426

[10]

ITO C, 1987, CHEM PHARM BULL, V35, P4277

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