Parahydrogen-induced polarization in imaging:: Subsecond 13C angiography

被引：288

作者：

Golman, K ^{[1
]}

Axelsson, O ^{[1
]}

Jóhannesson, H ^{[1
]}

Månsson, S ^{[1
]}

Olofsson, C ^{[1
]}

Petersson, JS ^{[1
]}

机构：

[1] Nycomed Innovat AB, MEDEON, SE-20512 Malmo, Sweden

来源：

MAGNETIC RESONANCE IN MEDICINE | 2001年 / 46卷 / 01期

关键词：

parahydrogen-induced polarization; diabatic; hyperpolarized C-13; angiography;

D O I：

10.1002/mrm.1152

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

High nuclear spin polarization of C-13 was reached in organic molecules. Enhancements of up to 10(4), compared to thermal polarization at 1.5 T, were achieved using the parahydrogen-induced polarization technique in combination with a field cycling method. While parahydrogen has no net polarization, it has a high spin order, which is retained when hydrogen is incorporated into another molecule by a chemical reaction. By subjecting this molecule to a sudden change of the external magnetic field, the spin order is transferred into net polarization. A C-13 angiogram of an animal was generated in less than a second. (C) 2001 Wiley-Liss, Inc.

引用

页码：1 / 5

页数：5

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