Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties

被引:165
作者
Cargnin, Simone Tasca [1 ]
Gnoatto, Simone Baggio [1 ]
机构
[1] Univ Fed Rio Grande do Sul, Sch Pharm, Phytochem & Organ Synth Lab, Porto Alegre, RS, Brazil
关键词
Apple; Industrial waste; Terpenoids; Therapeutic potentials; Traditional plants; IN-VITRO; INDUCED APOPTOSIS; OLEANOLIC ACID; PENTACYCLIC TRITERPENOIDS; ANTILEISHMANIAL ACTIVITY; ANTIMALARIAL ACTIVITY; TRYPANOCIDAL ACTIVITY; CANCER CELLS; EXTRACTS; PATHWAY;
D O I
10.1016/j.foodchem.2016.10.029
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Apple juice production generates a large amount of residue comprising mainly peels, seeds, and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple production and thousands of tons of apple pomace are produced every year. This by-product is little explored, since it is a rich and heterogeneous mixture, containing interesting phytochemical groups. Among them, ursolic acid (UA) has attracted attention because of its therapeutic potential. UA is a pentacyclic triterpene found too in several traditional plants, and has shown several functional properties such as antibacterial, antiprotozoal, anti-inflammatory and antitumor. Therefore, this review attempts to shed some light on the economical viability of apple and apple pomace as sources of bioactive compounds, highlighting the UA extraction, and its main functional properties published in the last 5 years (2010-2015). (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:477 / 489
页数:13
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