68Ga-DOTATATE in Benign Prostate Hyperplasia

A 79-year-old man had carcinoid syndrome and bilateral pulmonary nodules, which were biopsy confirmed as well-differentiated neuroendocrine tumor. PET/CT with Ga-68-[DOTA-Tyr(3)]-octreotate (Ga-68-DOTATATE) showed multiple Ga-68-DOTATATE-avid bilateral pulmonary nodules, left hilar lymph node, as well as diffuse increased Ga-68-DOTATATE uptake in the prostate. A review of the history revealed that this patient had elevated prostate-specific antigen level. The prostate biopsy did not reveal evidence of prostate cancer but showed benign prostate hyperplasia.