Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain

被引：14
作者：
Barrett, C [1 ]
Guthrie, S [1 ]
机构：
[1] Kings Coll London, MRC, Ctr Dev Neurobiol, London SE1 1UL, England
来源：
MECHANISMS OF DEVELOPMENT | 2001年 / 106卷 / 1-2期
关键词：
axon guidance; hindbrain; cranial motor neurons; chemorepulsion; netrin-1; netrin receptors; UNC5H; 1; DCC; islet-1; MNR2; Nkx2.2;
D O I：
10.1016/S0925-4773(01)00415-4
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The axon guidance molecule netrin-1 has been implicated in the midline repulsion of developing cranial motor axons. We have examined expression patterns of the netrin receptors UNC5H1 and DCC in embryonic rat hindbrains, in combination with labelling of developing motor neurons. We found that UNC5H1 expression colocalised with a number of cranial motor neuron subpopulations front embryonic day 11 (E11) to E14, while DCC was expressed by motor neurons at E12. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：163 / 166
页数：4
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