Periprosthetic Knee Infections Treated with Irrigation and Debridement: Outcomes and Preoperative Predictive Factors

被引:46
作者
Triantafyllopoulos, Georgios K. [1 ]
Poultsides, Lazaros A. [1 ]
Zhang, Wei [2 ]
Sculco, Peter K. [1 ]
Ma, Yan [2 ]
Sculco, Thomas P. [1 ]
机构
[1] Cornell Univ, Hosp Special Surg, Weill Med Coll, Dept Orthopaed Surg,Div Adult Reconstruct & Joint, New York, NY 10021 USA
[2] George Washington Univ, Dept Epidemiol & Biostat, Washington, DC 20052 USA
关键词
periprosthetic joint infections; knee; irrigation; debridement; outcomes; predictive factors; PROSTHETIC JOINT INFECTIONS; TOTAL HIP; ARTHROSCOPIC DEBRIDEMENT; IMPLANT RETENTION; DAIR DEBRIDEMENT; 2-STAGE REVISION; ARTHROPLASTY; MANAGEMENT; MICROBIOLOGY; ANTIBIOTICS;
D O I
10.1016/j.arth.2014.10.026
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The role of irrigation and debridement (I&D) in the treatment of periprosthetic joint infections (PJI) of the knee remains controversial. Our purpose was to identify the success rate and factors determining outcome of I&D in those patients. Clinical characteristics of 78 patients with PJI of the knee treated with I&D were retrospectively reviewed. Implant retention at final follow-up was achieved in 43 patients (55.1%). Logistic regression analysis revealed that duration of symptoms >5 days and thyroid disease were independent predictors of I&D failure. Patients with methicillin-resistant staphylococcal infections had a success rate of 45.5% and significantly lower odds of success compared to patients with negative cultures. In selected patients, I&D is a reasonable option in the context of acute PJI of the knee. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:649 / 657
页数:9
相关论文
共 51 条
[21]   Infection Control Rate of Irrigation and D,bridement for Periprosthetic Joint Infection [J].
Koyonos, Loukas ;
Zmistowski, Benjamin ;
Della Valle, Craig J. ;
Parvizi, Javad .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2011, 469 (11) :3043-3048
[22]   Prosthetic joint-associated infections treated with DAIR (debridement, antibiotics, irrigation, and retention) Analysis of risk factors and local antibiotic carriers in 91 patients [J].
Kuiper, Jesse W. P. ;
Vos, Stan J. ;
Saouti, Rachid ;
Vergroesen, Diederik A. ;
Graat, Harm C. A. ;
Debets-Ossenkopp, Yvette J. ;
Peters, Edgar J. G. ;
Nolte, Peter A. .
ACTA ORTHOPAEDICA, 2013, 84 (04) :380-386
[23]   Two-stage Exchange Knee Arthroplasty Does Resistance of the Infecting Organism Influence the Outcome? [J].
Kurd, Mark F. ;
Ghanem, Elie ;
Steinbrecher, Jill ;
Parvizi, Javad .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2010, 468 (08) :2060-2066
[24]   Single- or Two-stage Revision for Infected Total Hip Arthroplasty? A Systematic Review of the Literature [J].
Leonard, Hugh A. C. ;
Liddle, Alexander D. ;
Burke, Orlaith ;
Murray, David W. ;
Pandit, Hemant .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2014, 472 (03) :1036-1042
[25]  
Leone James M, 2006, Instr Course Lect, V55, P449
[26]   Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus [J].
Li, Min ;
Diep, Binh An ;
Villaruz, Amer E. ;
Braughton, Kevin R. ;
Jiang, Xiaofei ;
DeLeo, Frank R. ;
Chambers, Henry F. ;
Lu, Yuan ;
Otto, Michael .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (14) :5883-5888
[27]   Outcome of prosthetic joint infections treated with debridement and retention of components [J].
Marculescu, CE ;
Berbari, EF ;
Hanssen, AD ;
Steckelberg, JM ;
Harmsen, SW ;
Mandrekar, JN ;
Osmon, DR .
CLINICAL INFECTIOUS DISEASES, 2006, 42 (04) :471-478
[28]   Treatment of Prosthetic Joint Infections: Validation of a Surgical Algorithm and Proposal of a Simplified Alternative [J].
Martel-Laferriere, Valerie ;
Laflamme, Pierre ;
Ghannoum, Marc ;
Fernandes, Julio ;
Di Iorio, Daniela ;
Lavergne, Valery .
JOURNAL OF ARTHROPLASTY, 2013, 28 (03) :395-400
[29]   Outcome of Acute Prosthetic Joint Infections Due to Gram-Negative Bacilli Treated with Open Debridement and Retention of the Prosthesis [J].
Martinez-Pastor, Juan C. ;
Munoz-Mahamud, Ernesto ;
Vilchez, Felix ;
Garcia-Ramiro, Sebastian ;
Bori, Guillem ;
Sierra, Josep ;
Martinez, Jose A. ;
Font, Lluis ;
Mensa, Josep ;
Soriano, Alex .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (11) :4772-4777
[30]   Outcome of penicillin-susceptible streptococcal prosthetic joint infection treated with debridement and retention of the prosthesis [J].
Meehan, AM ;
Osmon, DR ;
Duffy, MCT ;
Hanssen, AD ;
Keating, MR .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (07) :845-849